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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP27X
All Species:
13.33
Human Site:
Y418
Identified Species:
20.95
UniProt:
A6NNY8
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NNY8
NP_001138545.1
438
49630
Y418
S
E
G
Y
L
L
F
Y
H
K
Q
V
L
E
H
Chimpanzee
Pan troglodytes
XP_521085
711
79749
I670
S
G
H
Y
T
S
F
I
R
Q
Q
K
D
Q
W
Rhesus Macaque
Macaca mulatta
XP_001100790
710
79332
A687
D
D
A
I
I
T
K
A
T
I
E
D
L
L
Y
Dog
Lupus familis
XP_548999
579
65084
Y559
S
E
G
Y
L
L
F
Y
H
K
Q
V
L
E
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8CEG8
438
49580
Y418
S
E
G
Y
L
L
F
Y
H
K
Q
V
L
E
P
Rat
Rattus norvegicus
B2GUX4
565
62681
A546
P
V
S
E
N
Q
V
A
S
S
E
G
Y
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511206
488
55972
A465
D
D
A
I
I
T
K
A
S
I
K
D
V
L
D
Chicken
Gallus gallus
O57429
357
40913
V338
T
P
M
S
S
S
H
V
R
S
S
D
A
Y
L
Frog
Xenopus laevis
Q6GNI6
523
60030
A500
D
D
A
I
I
T
K
A
S
I
K
D
V
L
D
Zebra Danio
Brachydanio rerio
A6H8I0
506
58102
H468
Y
T
T
F
I
R
Q
H
K
D
Q
W
F
K
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVR1
735
82440
S713
D
H
V
I
T
M
A
S
L
K
Q
V
L
D
S
Honey Bee
Apis mellifera
XP_395389
502
57164
E483
L
K
D
V
L
T
S
E
G
Y
L
L
F
Y
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786312
585
65894
C506
S
E
G
F
I
I
I
C
T
F
S
S
T
T
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LEW0
557
63499
Y528
C
E
C
Y
M
L
F
Y
A
Q
E
T
V
I
Q
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
C432
E
G
H
Y
I
A
F
C
K
I
S
G
G
Q
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.5
45.2
74.6
N.A.
96.3
20.1
N.A.
73.5
23.7
65.7
65.8
N.A.
26.5
53.3
N.A.
46.8
Protein Similarity:
100
51.9
51.2
75.1
N.A.
97.7
34.3
N.A.
79
39.5
71.6
72.9
N.A.
38.2
65.7
N.A.
59.4
P-Site Identity:
100
26.6
6.6
100
N.A.
93.3
0
N.A.
0
0
0
6.6
N.A.
26.6
13.3
N.A.
20
P-Site Similarity:
100
40
33.3
100
N.A.
93.3
6.6
N.A.
26.6
6.6
26.6
33.3
N.A.
40
26.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.7
23.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.8
40.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
20
0
0
7
7
27
7
0
0
0
7
0
0
% A
% Cys:
7
0
7
0
0
0
0
14
0
0
0
0
0
0
7
% C
% Asp:
27
20
7
0
0
0
0
0
0
7
0
27
7
7
14
% D
% Glu:
7
34
0
7
0
0
0
7
0
0
20
0
0
20
0
% E
% Phe:
0
0
0
14
0
0
40
0
0
7
0
0
14
0
0
% F
% Gly:
0
14
27
0
0
0
0
0
7
0
0
14
7
0
0
% G
% His:
0
7
14
0
0
0
7
7
20
0
0
0
0
0
20
% H
% Ile:
0
0
0
27
40
7
7
7
0
27
0
0
0
7
0
% I
% Lys:
0
7
0
0
0
0
20
0
14
27
14
7
0
7
0
% K
% Leu:
7
0
0
0
27
27
0
0
7
0
7
7
34
20
14
% L
% Met:
0
0
7
0
7
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
7
7
0
0
0
0
0
0
0
0
0
0
0
0
7
% P
% Gln:
0
0
0
0
0
7
7
0
0
14
40
0
0
14
7
% Q
% Arg:
0
0
0
0
0
7
0
0
14
0
0
0
0
0
7
% R
% Ser:
34
0
7
7
7
14
7
7
20
14
20
7
0
0
7
% S
% Thr:
7
7
7
0
14
27
0
0
14
0
0
7
7
7
0
% T
% Val:
0
7
7
7
0
0
7
7
0
0
0
27
20
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
14
% W
% Tyr:
7
0
0
40
0
0
0
27
0
7
0
0
7
14
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _