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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TTLL8 All Species: 16.06
Human Site: S127 Identified Species: 44.17
UniProt: A6PVC2 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6PVC2 NP_001073916 814 90756 S127 N H Y A K T A S F T T K I G L
Chimpanzee Pan troglodytes XP_517039 903 101959 S142 N H Y A R A G S F T T K V G L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_531691 697 79410 Y100 C D Q M L N H Y G K T A S F T
Cat Felis silvestris
Mouse Mus musculus A4Q9F1 832 94897 S208 N H Y G K T A S F T T K I G L
Rat Rattus norvegicus XP_001076771 590 67353
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q1ECV4 771 88857 S154 N H Y A K A G S F T T K V G L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VM91 992 112237 F250 N K F H R A P F T S K E G L C
Honey Bee Apis mellifera XP_393908 735 84876 I108 N A D A S P I I L L A G I G D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784103 1146 128055 T441 N H F C K N G T F T T K V G L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 38.8 N.A. 64.3 N.A. 59.2 35.7 N.A. N.A. N.A. N.A. 38.2 N.A. 25.2 29.7 N.A. 27.4
Protein Similarity: 100 53.5 N.A. 72.7 N.A. 70.9 49 N.A. N.A. N.A. N.A. 56.2 N.A. 40.5 49.3 N.A. 40.6
P-Site Identity: 100 73.3 N.A. 6.6 N.A. 93.3 0 N.A. N.A. N.A. N.A. 80 N.A. 6.6 26.6 N.A. 60
P-Site Similarity: 100 86.6 N.A. 6.6 N.A. 93.3 0 N.A. N.A. N.A. N.A. 86.6 N.A. 33.3 26.6 N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 0 45 0 34 23 0 0 0 12 12 0 0 0 % A
% Cys: 12 0 0 12 0 0 0 0 0 0 0 0 0 0 12 % C
% Asp: 0 12 12 0 0 0 0 0 0 0 0 0 0 0 12 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % E
% Phe: 0 0 23 0 0 0 0 12 56 0 0 0 0 12 0 % F
% Gly: 0 0 0 12 0 0 34 0 12 0 0 12 12 67 0 % G
% His: 0 56 0 12 0 0 12 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 12 12 0 0 0 0 34 0 0 % I
% Lys: 0 12 0 0 45 0 0 0 0 12 12 56 0 0 0 % K
% Leu: 0 0 0 0 12 0 0 0 12 12 0 0 0 12 56 % L
% Met: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 78 0 0 0 0 23 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 12 12 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 23 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 12 0 0 45 0 12 0 0 12 0 0 % S
% Thr: 0 0 0 0 0 23 0 12 12 56 67 0 0 0 12 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 34 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 45 0 0 0 0 12 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _