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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTLL8
All Species:
15.76
Human Site:
S397
Identified Species:
43.33
UniProt:
A6PVC2
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6PVC2
NP_001073916
814
90756
S397
K
E
S
Y
L
R
F
S
T
Q
R
F
S
L
D
Chimpanzee
Pan troglodytes
XP_517039
903
101959
S403
R
D
S
Y
I
R
F
S
T
Q
P
F
S
L
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_531691
697
79410
F344
L
L
I
Y
D
T
K
F
D
I
R
Q
W
F
L
Cat
Felis silvestris
Mouse
Mus musculus
A4Q9F1
832
94897
S476
K
E
S
Y
L
R
F
S
T
Q
R
F
S
L
D
Rat
Rattus norvegicus
XP_001076771
590
67353
L237
G
I
T
C
M
D
H
L
D
E
M
L
K
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1ECV4
771
88857
S418
R
E
C
Y
L
R
F
S
T
Q
P
Y
S
T
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VM91
992
112237
S498
R
E
S
Y
L
R
F
S
S
Q
E
Y
S
L
S
Honey Bee
Apis mellifera
XP_393908
735
84876
N359
E
D
V
M
A
K
M
N
P
S
T
K
S
D
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784103
1146
128055
C699
D
A
C
Y
L
R
F
C
T
Q
P
F
S
L
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
38.8
N.A.
64.3
N.A.
59.2
35.7
N.A.
N.A.
N.A.
N.A.
38.2
N.A.
25.2
29.7
N.A.
27.4
Protein Similarity:
100
53.5
N.A.
72.7
N.A.
70.9
49
N.A.
N.A.
N.A.
N.A.
56.2
N.A.
40.5
49.3
N.A.
40.6
P-Site Identity:
100
66.6
N.A.
13.3
N.A.
100
6.6
N.A.
N.A.
N.A.
N.A.
60
N.A.
66.6
6.6
N.A.
66.6
P-Site Similarity:
100
86.6
N.A.
13.3
N.A.
100
26.6
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
86.6
33.3
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
0
12
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
23
12
0
0
0
12
0
0
0
0
0
0
0
% C
% Asp:
12
23
0
0
12
12
0
0
23
0
0
0
0
12
34
% D
% Glu:
12
45
0
0
0
0
0
0
0
12
12
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
67
12
0
0
0
45
0
12
0
% F
% Gly:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
12
% H
% Ile:
0
12
12
0
12
0
0
0
0
12
0
0
0
0
0
% I
% Lys:
23
0
0
0
0
12
12
0
0
0
0
12
12
0
12
% K
% Leu:
12
12
0
0
56
0
0
12
0
0
0
12
0
67
12
% L
% Met:
0
0
0
12
12
0
12
0
0
0
12
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
12
0
34
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
67
0
12
0
0
0
% Q
% Arg:
34
0
0
0
0
67
0
0
0
0
34
0
0
0
0
% R
% Ser:
0
0
45
0
0
0
0
56
12
12
0
0
78
0
12
% S
% Thr:
0
0
12
0
0
12
0
0
56
0
12
0
0
12
12
% T
% Val:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% W
% Tyr:
0
0
0
78
0
0
0
0
0
0
0
23
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _