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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TTLL8 All Species: 5.76
Human Site: S428 Identified Species: 15.83
UniProt: A6PVC2 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6PVC2 NP_001073916 814 90756 S428 L K N D V G R S P L L P A H N
Chimpanzee Pan troglodytes XP_517039 903 101959 H434 L E N S C H R H P L L P P D N
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_531691 697 79410 F375 L R F S T Q R F S L E N L D S
Cat Felis silvestris
Mouse Mus musculus A4Q9F1 832 94897 S507 L K N D K E R S P L L P C H N
Rat Rattus norvegicus XP_001076771 590 67353 I268 Y I E R P L L I F G T K F D L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q1ECV4 771 88857 S449 Y Q P S P D R S P S L P A E C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VM91 992 112237 K529 Y T N G K R D K R L P S E N M
Honey Bee Apis mellifera XP_393908 735 84876 W390 T K F D I R Q W F I I T C S Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784103 1146 128055 D730 Y D N A V E R D E N L P Y D N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 38.8 N.A. 64.3 N.A. 59.2 35.7 N.A. N.A. N.A. N.A. 38.2 N.A. 25.2 29.7 N.A. 27.4
Protein Similarity: 100 53.5 N.A. 72.7 N.A. 70.9 49 N.A. N.A. N.A. N.A. 56.2 N.A. 40.5 49.3 N.A. 40.6
P-Site Identity: 100 53.3 N.A. 20 N.A. 80 0 N.A. N.A. N.A. N.A. 40 N.A. 13.3 13.3 N.A. 40
P-Site Similarity: 100 60 N.A. 33.3 N.A. 80 0 N.A. N.A. N.A. N.A. 46.6 N.A. 20 40 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 12 0 0 0 0 0 0 0 0 23 0 0 % A
% Cys: 0 0 0 0 12 0 0 0 0 0 0 0 23 0 12 % C
% Asp: 0 12 0 34 0 12 12 12 0 0 0 0 0 45 0 % D
% Glu: 0 12 12 0 0 23 0 0 12 0 12 0 12 12 0 % E
% Phe: 0 0 23 0 0 0 0 12 23 0 0 0 12 0 0 % F
% Gly: 0 0 0 12 0 12 0 0 0 12 0 0 0 0 0 % G
% His: 0 0 0 0 0 12 0 12 0 0 0 0 0 23 0 % H
% Ile: 0 12 0 0 12 0 0 12 0 12 12 0 0 0 0 % I
% Lys: 0 34 0 0 23 0 0 12 0 0 0 12 0 0 0 % K
% Leu: 45 0 0 0 0 12 12 0 0 56 56 0 12 0 12 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % M
% Asn: 0 0 56 0 0 0 0 0 0 12 0 12 0 12 45 % N
% Pro: 0 0 12 0 23 0 0 0 45 0 12 56 12 0 0 % P
% Gln: 0 12 0 0 0 12 12 0 0 0 0 0 0 0 12 % Q
% Arg: 0 12 0 12 0 23 67 0 12 0 0 0 0 0 0 % R
% Ser: 0 0 0 34 0 0 0 34 12 12 0 12 0 12 12 % S
% Thr: 12 12 0 0 12 0 0 0 0 0 12 12 0 0 0 % T
% Val: 0 0 0 0 23 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % W
% Tyr: 45 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _