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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTLL8
All Species:
10.3
Human Site:
S457
Identified Species:
28.33
UniProt:
A6PVC2
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6PVC2
NP_001073916
814
90756
S457
G
R
G
A
V
W
G
S
V
I
Y
P
S
M
K
Chimpanzee
Pan troglodytes
XP_517039
903
101959
T463
G
A
P
N
A
W
S
T
I
I
V
P
G
M
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_531691
697
79410
L404
N
D
K
D
R
S
P
L
L
P
Y
H
N
M
W
Cat
Felis silvestris
Mouse
Mus musculus
A4Q9F1
832
94897
S536
G
R
G
G
T
W
G
S
I
I
Y
P
S
M
K
Rat
Rattus norvegicus
XP_001076771
590
67353
I297
W
F
Y
R
D
S
Y
I
R
F
S
T
Q
P
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1ECV4
771
88857
A478
G
R
A
A
L
W
K
A
V
V
V
P
G
M
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VM91
992
112237
R558
K
Y
N
M
W
L
E
R
I
F
P
G
M
R
K
Honey Bee
Apis mellifera
XP_393908
735
84876
T419
C
S
Q
K
F
S
L
T
D
F
H
E
S
I
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784103
1146
128055
S759
G
F
E
G
L
W
E
S
V
I
V
P
G
M
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
38.8
N.A.
64.3
N.A.
59.2
35.7
N.A.
N.A.
N.A.
N.A.
38.2
N.A.
25.2
29.7
N.A.
27.4
Protein Similarity:
100
53.5
N.A.
72.7
N.A.
70.9
49
N.A.
N.A.
N.A.
N.A.
56.2
N.A.
40.5
49.3
N.A.
40.6
P-Site Identity:
100
40
N.A.
13.3
N.A.
80
0
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
6.6
6.6
N.A.
53.3
P-Site Similarity:
100
53.3
N.A.
26.6
N.A.
86.6
0
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
13.3
26.6
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
12
23
12
0
0
12
0
0
0
0
0
0
0
% A
% Cys:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
0
12
12
0
0
0
12
0
0
0
0
0
0
% D
% Glu:
0
0
12
0
0
0
23
0
0
0
0
12
0
0
0
% E
% Phe:
0
23
0
0
12
0
0
0
0
34
0
0
0
0
12
% F
% Gly:
56
0
23
23
0
0
23
0
0
0
0
12
34
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
12
12
0
0
12
% H
% Ile:
0
0
0
0
0
0
0
12
34
45
0
0
0
12
0
% I
% Lys:
12
0
12
12
0
0
12
0
0
0
0
0
0
0
56
% K
% Leu:
0
0
0
0
23
12
12
12
12
0
0
0
0
0
0
% L
% Met:
0
0
0
12
0
0
0
0
0
0
0
0
12
67
0
% M
% Asn:
12
0
12
12
0
0
0
0
0
0
0
0
12
0
0
% N
% Pro:
0
0
12
0
0
0
12
0
0
12
12
56
0
12
0
% P
% Gln:
0
0
12
0
0
0
0
0
0
0
0
0
12
0
12
% Q
% Arg:
0
34
0
12
12
0
0
12
12
0
0
0
0
12
0
% R
% Ser:
0
12
0
0
0
34
12
34
0
0
12
0
34
0
0
% S
% Thr:
0
0
0
0
12
0
0
23
0
0
0
12
0
0
0
% T
% Val:
0
0
0
0
12
0
0
0
34
12
34
0
0
0
0
% V
% Trp:
12
0
0
0
12
56
0
0
0
0
0
0
0
0
12
% W
% Tyr:
0
12
12
0
0
0
12
0
0
0
34
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _