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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTLL8
All Species:
1.21
Human Site:
T718
Identified Species:
3.33
UniProt:
A6PVC2
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6PVC2
NP_001073916
814
90756
T718
P
G
G
K
G
E
G
T
V
C
S
R
L
P
H
Chimpanzee
Pan troglodytes
XP_517039
903
101959
P804
P
T
A
L
V
L
D
P
T
P
N
K
K
K
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_531691
697
79410
Q623
A
E
R
N
C
K
V
Q
S
A
N
A
E
S
G
Cat
Felis silvestris
Mouse
Mus musculus
A4Q9F1
832
94897
P757
R
V
Q
S
S
K
V
P
G
V
T
L
T
S
A
Rat
Rattus norvegicus
XP_001076771
590
67353
K516
H
F
P
S
L
H
I
K
A
W
L
P
S
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1ECV4
771
88857
S697
L
S
H
T
Q
P
Q
S
D
R
P
H
T
H
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VM91
992
112237
L905
P
S
L
P
T
R
R
L
T
R
T
K
S
E
I
Honey Bee
Apis mellifera
XP_393908
735
84876
S658
L
R
Q
A
L
P
M
S
I
R
P
K
S
L
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784103
1146
128055
C1046
T
S
E
V
S
D
G
C
E
N
N
C
D
T
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
38.8
N.A.
64.3
N.A.
59.2
35.7
N.A.
N.A.
N.A.
N.A.
38.2
N.A.
25.2
29.7
N.A.
27.4
Protein Similarity:
100
53.5
N.A.
72.7
N.A.
70.9
49
N.A.
N.A.
N.A.
N.A.
56.2
N.A.
40.5
49.3
N.A.
40.6
P-Site Identity:
100
6.6
N.A.
0
N.A.
0
6.6
N.A.
N.A.
N.A.
N.A.
0
N.A.
6.6
0
N.A.
6.6
P-Site Similarity:
100
20
N.A.
13.3
N.A.
13.3
6.6
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
20
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
12
12
0
0
0
0
12
12
0
12
0
0
12
% A
% Cys:
0
0
0
0
12
0
0
12
0
12
0
12
0
0
0
% C
% Asp:
0
0
0
0
0
12
12
0
12
0
0
0
12
0
0
% D
% Glu:
0
12
12
0
0
12
0
0
12
0
0
0
12
12
0
% E
% Phe:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
12
% F
% Gly:
0
12
12
0
12
0
23
0
12
0
0
0
0
0
12
% G
% His:
12
0
12
0
0
12
0
0
0
0
0
12
0
12
12
% H
% Ile:
0
0
0
0
0
0
12
0
12
0
0
0
0
0
23
% I
% Lys:
0
0
0
12
0
23
0
12
0
0
0
34
12
12
0
% K
% Leu:
23
0
12
12
23
12
0
12
0
0
12
12
12
12
0
% L
% Met:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
12
0
0
0
0
0
12
34
0
0
0
0
% N
% Pro:
34
0
12
12
0
23
0
23
0
12
23
12
0
23
0
% P
% Gln:
0
0
23
0
12
0
12
12
0
0
0
0
0
0
12
% Q
% Arg:
12
12
12
0
0
12
12
0
0
34
0
12
0
0
23
% R
% Ser:
0
34
0
23
23
0
0
23
12
0
12
0
34
23
0
% S
% Thr:
12
12
0
12
12
0
0
12
23
0
23
0
23
12
0
% T
% Val:
0
12
0
12
12
0
23
0
12
12
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _