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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTLL8
All Species:
4.24
Human Site:
Y144
Identified Species:
11.67
UniProt:
A6PVC2
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6PVC2
NP_001073916
814
90756
Y144
N
M
R
S
L
P
W
Y
V
P
A
N
P
D
S
Chimpanzee
Pan troglodytes
XP_517039
903
101959
F159
N
L
R
N
L
P
W
F
D
E
V
D
A
N
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_531691
697
79410
R117
I
G
L
C
V
N
M
R
S
L
P
W
Y
V
Q
Cat
Felis silvestris
Mouse
Mus musculus
A4Q9F1
832
94897
Y225
N
M
R
S
L
P
W
Y
V
Q
A
N
P
N
T
Rat
Rattus norvegicus
XP_001076771
590
67353
I10
R
N
E
T
P
Y
L
I
W
T
T
R
R
D
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1ECV4
771
88857
F171
H
L
R
N
L
Q
W
F
D
A
A
D
P
D
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VM91
992
112237
F267
L
R
D
F
H
W
F
F
E
E
G
T
A
E
M
Honey Bee
Apis mellifera
XP_393908
735
84876
L125
D
Q
Q
S
E
R
L
L
I
S
K
M
L
T
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784103
1146
128055
F458
S
L
K
N
L
P
W
F
E
E
R
E
A
E
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
38.8
N.A.
64.3
N.A.
59.2
35.7
N.A.
N.A.
N.A.
N.A.
38.2
N.A.
25.2
29.7
N.A.
27.4
Protein Similarity:
100
53.5
N.A.
72.7
N.A.
70.9
49
N.A.
N.A.
N.A.
N.A.
56.2
N.A.
40.5
49.3
N.A.
40.6
P-Site Identity:
100
40
N.A.
0
N.A.
80
6.6
N.A.
N.A.
N.A.
N.A.
40
N.A.
0
6.6
N.A.
20
P-Site Similarity:
100
73.3
N.A.
6.6
N.A.
93.3
13.3
N.A.
N.A.
N.A.
N.A.
80
N.A.
20
33.3
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
12
34
0
34
0
0
% A
% Cys:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
12
0
0
0
0
0
23
0
0
23
0
34
0
% D
% Glu:
0
0
12
0
12
0
0
0
23
34
0
12
0
23
0
% E
% Phe:
0
0
0
12
0
0
12
45
0
0
0
0
0
0
0
% F
% Gly:
0
12
0
0
0
0
0
0
0
0
12
0
0
0
0
% G
% His:
12
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
0
0
0
0
0
0
12
12
0
0
0
0
0
0
% I
% Lys:
0
0
12
0
0
0
0
0
0
0
12
0
0
0
0
% K
% Leu:
12
34
12
0
56
0
23
12
0
12
0
0
12
0
0
% L
% Met:
0
23
0
0
0
0
12
0
0
0
0
12
0
0
12
% M
% Asn:
34
12
0
34
0
12
0
0
0
0
0
23
0
23
12
% N
% Pro:
0
0
0
0
12
45
0
0
0
12
12
0
34
0
0
% P
% Gln:
0
12
12
0
0
12
0
0
0
12
0
0
0
0
12
% Q
% Arg:
12
12
45
0
0
12
0
12
0
0
12
12
12
0
0
% R
% Ser:
12
0
0
34
0
0
0
0
12
12
0
0
0
0
23
% S
% Thr:
0
0
0
12
0
0
0
0
0
12
12
12
0
12
34
% T
% Val:
0
0
0
0
12
0
0
0
23
0
12
0
0
12
12
% V
% Trp:
0
0
0
0
0
12
56
0
12
0
0
12
0
0
0
% W
% Tyr:
0
0
0
0
0
12
0
23
0
0
0
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _