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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTLL8
All Species:
11.52
Human Site:
Y272
Identified Species:
31.67
UniProt:
A6PVC2
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6PVC2
NP_001073916
814
90756
Y272
W
E
D
L
T
Q
Q
Y
Y
S
L
V
H
G
D
Chimpanzee
Pan troglodytes
XP_517039
903
101959
Y278
W
S
L
F
L
Q
R
Y
Y
Q
V
V
H
E
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_531691
697
79410
S231
I
D
V
S
E
D
A
S
E
D
L
T
E
D
E
Cat
Felis silvestris
Mouse
Mus musculus
A4Q9F1
832
94897
Y351
W
N
D
L
T
Q
Q
Y
Y
L
L
V
H
G
N
Rat
Rattus norvegicus
XP_001076771
590
67353
K124
T
Q
P
K
K
Q
E
K
K
P
V
T
V
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1ECV4
771
88857
Y293
W
K
V
F
L
Q
N
Y
Y
L
V
V
H
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VM91
992
112237
Q381
V
N
E
D
G
R
I
Q
H
D
G
G
Q
R
L
Honey Bee
Apis mellifera
XP_393908
735
84876
V242
V
R
S
P
T
G
T
V
P
L
K
A
L
E
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784103
1146
128055
Y575
W
D
K
F
I
T
E
Y
Y
Q
L
T
S
E
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
38.8
N.A.
64.3
N.A.
59.2
35.7
N.A.
N.A.
N.A.
N.A.
38.2
N.A.
25.2
29.7
N.A.
27.4
Protein Similarity:
100
53.5
N.A.
72.7
N.A.
70.9
49
N.A.
N.A.
N.A.
N.A.
56.2
N.A.
40.5
49.3
N.A.
40.6
P-Site Identity:
100
40
N.A.
6.6
N.A.
80
6.6
N.A.
N.A.
N.A.
N.A.
40
N.A.
0
6.6
N.A.
26.6
P-Site Similarity:
100
53.3
N.A.
20
N.A.
86.6
26.6
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
20
6.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
12
0
0
0
0
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
23
23
12
0
12
0
0
0
23
0
0
0
12
12
% D
% Glu:
0
12
12
0
12
0
23
0
12
0
0
0
12
45
12
% E
% Phe:
0
0
0
34
0
0
0
0
0
0
0
0
0
0
12
% F
% Gly:
0
0
0
0
12
12
0
0
0
0
12
12
0
23
23
% G
% His:
0
0
0
0
0
0
0
0
12
0
0
0
45
0
0
% H
% Ile:
12
0
0
0
12
0
12
0
0
0
0
0
0
0
0
% I
% Lys:
0
12
12
12
12
0
0
12
12
0
12
0
0
0
0
% K
% Leu:
0
0
12
23
23
0
0
0
0
34
45
0
12
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
23
0
0
0
0
12
0
0
0
0
0
0
0
12
% N
% Pro:
0
0
12
12
0
0
0
0
12
12
0
0
0
0
0
% P
% Gln:
0
12
0
0
0
56
23
12
0
23
0
0
12
0
0
% Q
% Arg:
0
12
0
0
0
12
12
0
0
0
0
0
0
12
12
% R
% Ser:
0
12
12
12
0
0
0
12
0
12
0
0
12
12
12
% S
% Thr:
12
0
0
0
34
12
12
0
0
0
0
34
0
0
0
% T
% Val:
23
0
23
0
0
0
0
12
0
0
34
45
12
0
0
% V
% Trp:
56
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
56
56
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _