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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTLL8
All Species:
8.48
Human Site:
Y445
Identified Species:
23.33
UniProt:
A6PVC2
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6PVC2
NP_001073916
814
90756
Y445
T
S
T
R
F
Q
E
Y
L
Q
R
Q
G
R
G
Chimpanzee
Pan troglodytes
XP_517039
903
101959
H451
S
S
R
R
F
Q
A
H
L
Q
E
M
G
A
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_531691
697
79410
Q392
H
L
C
N
N
S
I
Q
K
H
L
K
N
D
K
Cat
Felis silvestris
Mouse
Mus musculus
A4Q9F1
832
94897
Y524
T
S
T
R
F
Q
E
Y
L
Q
K
R
G
R
G
Rat
Rattus norvegicus
XP_001076771
590
67353
N285
W
F
L
V
T
D
W
N
P
L
T
V
W
F
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1ECV4
771
88857
W466
S
C
S
Q
F
R
S
W
L
A
A
S
G
R
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VM91
992
112237
L546
C
Y
S
F
Q
A
Y
L
R
Q
I
G
K
Y
N
Honey Bee
Apis mellifera
XP_393908
735
84876
S407
T
L
W
I
Y
R
E
S
Y
L
R
F
C
S
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784103
1146
128055
Y747
D
S
D
T
F
R
K
Y
L
D
D
R
G
F
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
38.8
N.A.
64.3
N.A.
59.2
35.7
N.A.
N.A.
N.A.
N.A.
38.2
N.A.
25.2
29.7
N.A.
27.4
Protein Similarity:
100
53.5
N.A.
72.7
N.A.
70.9
49
N.A.
N.A.
N.A.
N.A.
56.2
N.A.
40.5
49.3
N.A.
40.6
P-Site Identity:
100
46.6
N.A.
0
N.A.
86.6
0
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
6.6
20
N.A.
33.3
P-Site Similarity:
100
60
N.A.
6.6
N.A.
100
0
N.A.
N.A.
N.A.
N.A.
60
N.A.
13.3
33.3
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
12
12
0
0
12
12
0
0
12
12
% A
% Cys:
12
12
12
0
0
0
0
0
0
0
0
0
12
0
0
% C
% Asp:
12
0
12
0
0
12
0
0
0
12
12
0
0
12
0
% D
% Glu:
0
0
0
0
0
0
34
0
0
0
12
0
0
0
12
% E
% Phe:
0
12
0
12
56
0
0
0
0
0
0
12
0
23
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
12
56
0
23
% G
% His:
12
0
0
0
0
0
0
12
0
12
0
0
0
0
0
% H
% Ile:
0
0
0
12
0
0
12
0
0
0
12
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
12
0
12
0
12
12
12
0
12
% K
% Leu:
0
23
12
0
0
0
0
12
56
23
12
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% M
% Asn:
0
0
0
12
12
0
0
12
0
0
0
0
12
0
12
% N
% Pro:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
12
% P
% Gln:
0
0
0
12
12
34
0
12
0
45
0
12
0
0
12
% Q
% Arg:
0
0
12
34
0
34
0
0
12
0
23
23
0
34
0
% R
% Ser:
23
45
23
0
0
12
12
12
0
0
0
12
0
12
0
% S
% Thr:
34
0
23
12
12
0
0
0
0
0
12
0
0
0
0
% T
% Val:
0
0
0
12
0
0
0
0
0
0
0
12
0
0
0
% V
% Trp:
12
0
12
0
0
0
12
12
0
0
0
0
12
0
0
% W
% Tyr:
0
12
0
0
12
0
12
34
12
0
0
0
0
12
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _