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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTLL8
All Species:
14.85
Human Site:
Y98
Identified Species:
40.83
UniProt:
A6PVC2
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6PVC2
NP_001073916
814
90756
Y98
L
V
K
N
E
M
P
Y
L
L
W
T
I
K
R
Chimpanzee
Pan troglodytes
XP_517039
903
101959
Y113
M
V
Q
N
E
T
P
Y
F
I
W
T
T
R
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_531691
697
79410
K71
D
V
M
S
R
L
V
K
N
E
V
P
Y
L
L
Cat
Felis silvestris
Mouse
Mus musculus
A4Q9F1
832
94897
Y179
L
V
K
N
E
I
P
Y
L
L
W
T
I
K
R
Rat
Rattus norvegicus
XP_001076771
590
67353
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1ECV4
771
88857
Y125
L
V
R
H
E
T
P
Y
F
Y
W
T
T
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VM91
992
112237
L221
E
H
M
P
V
D
F
L
W
T
N
R
K
E
K
Honey Bee
Apis mellifera
XP_393908
735
84876
C79
R
A
R
V
I
R
E
C
M
L
K
R
G
W
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784103
1146
128055
S412
I
V
R
N
A
T
P
S
F
L
W
T
V
R
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
38.8
N.A.
64.3
N.A.
59.2
35.7
N.A.
N.A.
N.A.
N.A.
38.2
N.A.
25.2
29.7
N.A.
27.4
Protein Similarity:
100
53.5
N.A.
72.7
N.A.
70.9
49
N.A.
N.A.
N.A.
N.A.
56.2
N.A.
40.5
49.3
N.A.
40.6
P-Site Identity:
100
53.3
N.A.
6.6
N.A.
93.3
0
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
0
6.6
N.A.
40
P-Site Similarity:
100
80
N.A.
20
N.A.
100
0
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
13.3
20
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
0
12
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
12
% C
% Asp:
12
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% D
% Glu:
12
0
0
0
45
0
12
0
0
12
0
0
0
12
0
% E
% Phe:
0
0
0
0
0
0
12
0
34
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% G
% His:
0
12
0
12
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
0
0
0
12
12
0
0
0
12
0
0
23
0
0
% I
% Lys:
0
0
23
0
0
0
0
12
0
0
12
0
12
23
23
% K
% Leu:
34
0
0
0
0
12
0
12
23
45
0
0
0
12
12
% L
% Met:
12
0
23
0
0
12
0
0
12
0
0
0
0
0
0
% M
% Asn:
0
0
0
45
0
0
0
0
12
0
12
0
0
0
0
% N
% Pro:
0
0
0
12
0
0
56
0
0
0
0
12
0
0
0
% P
% Gln:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
12
0
34
0
12
12
0
0
0
0
0
23
0
34
45
% R
% Ser:
0
0
0
12
0
0
0
12
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
34
0
0
0
12
0
56
23
0
0
% T
% Val:
0
67
0
12
12
0
12
0
0
0
12
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
12
0
56
0
0
12
0
% W
% Tyr:
0
0
0
0
0
0
0
45
0
12
0
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _