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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM177B All Species: 8.18
Human Site: S119 Identified Species: 18
UniProt: A6PVY3 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.5
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6PVY3 NP_997351.2 158 18145 S119 N K K S D N K S E R R G S K A
Chimpanzee Pan troglodytes XP_001158779 158 18089 S119 N K K S D N K S E R K G S K A
Rhesus Macaque Macaca mulatta XP_001096130 148 17183 V112 A Q Q F L P E V E R G C L E S
Dog Lupus familis XP_536150 173 19823 S119 S K E S D K E S E G D G S K A
Cat Felis silvestris
Mouse Mus musculus Q8BR63 207 23560 E146 K E E E E E E E E N R M S E E
Rat Rattus norvegicus XP_002729670 209 23751 E147 K E E E E E E E E N R M S E E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512165 153 17742 D118 Y Y R T Q N Q D R D S E S E G
Chicken Gallus gallus NP_001026373 213 23955 Q149 K E E E E E E Q E N R M S E E
Frog Xenopus laevis NP_001086911 188 21440 E125 K E T E E E E E E N E M S E K
Zebra Danio Brachydanio rerio NP_001038926 134 15604 I102 R M A S L F G I T S A K Y Q Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787031 219 24349 D180 K E E K E E L D R Q M A E R E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.8 58.8 69.9 N.A. 30.4 30.1 N.A. 55.7 31.4 33.5 35.4 N.A. N.A. N.A. N.A. 24.6
Protein Similarity: 100 98.7 67 78.6 N.A. 51.6 49.7 N.A. 67.7 49.7 53.7 55.7 N.A. N.A. N.A. N.A. 41.5
P-Site Identity: 100 93.3 13.3 60 N.A. 20 20 N.A. 13.3 20 13.3 6.6 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 46.6 80 N.A. 53.3 53.3 N.A. 40 53.3 40 13.3 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 0 0 0 0 0 0 0 10 10 0 0 28 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % C
% Asp: 0 0 0 0 28 0 0 19 0 10 10 0 0 0 0 % D
% Glu: 0 46 46 37 46 46 55 28 73 0 10 10 10 55 37 % E
% Phe: 0 0 0 10 0 10 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 10 0 0 10 10 28 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % I
% Lys: 46 28 19 10 0 10 19 0 0 0 10 10 0 28 10 % K
% Leu: 0 0 0 0 19 0 10 0 0 0 0 0 10 0 0 % L
% Met: 0 10 0 0 0 0 0 0 0 0 10 37 0 0 0 % M
% Asn: 19 0 0 0 0 28 0 0 0 37 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 10 10 0 10 0 10 10 0 10 0 0 0 10 0 % Q
% Arg: 10 0 10 0 0 0 0 0 19 28 37 0 0 10 0 % R
% Ser: 10 0 0 37 0 0 0 28 0 10 10 0 73 0 10 % S
% Thr: 0 0 10 10 0 0 0 0 10 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 10 0 0 0 0 0 0 0 0 0 0 10 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _