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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM177B
All Species:
8.48
Human Site:
T21
Identified Species:
18.67
UniProt:
A6PVY3
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6PVY3
NP_997351.2
158
18145
T21
S
V
P
S
K
K
T
T
P
K
R
I
I
H
F
Chimpanzee
Pan troglodytes
XP_001158779
158
18089
T21
S
V
P
S
K
K
T
T
P
E
R
I
I
H
F
Rhesus Macaque
Macaca mulatta
XP_001096130
148
17183
V15
Q
L
D
L
E
K
S
V
P
S
K
K
T
T
P
Dog
Lupus familis
XP_536150
173
19823
T21
S
G
S
S
K
R
T
T
P
K
R
I
I
H
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8BR63
207
23560
V48
V
M
G
K
K
K
K
V
P
R
R
V
I
H
F
Rat
Rattus norvegicus
XP_002729670
209
23751
V49
V
M
G
K
K
K
K
V
P
R
R
V
I
H
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512165
153
17742
G19
S
F
Q
Q
P
E
P
G
D
K
G
L
T
N
T
Chicken
Gallus gallus
NP_001026373
213
23955
V52
V
I
G
K
K
K
K
V
P
R
R
V
I
H
F
Frog
Xenopus laevis
NP_001086911
188
21440
I28
D
I
R
K
K
K
K
I
P
R
R
V
I
H
F
Zebra Danio
Brachydanio rerio
NP_001038926
134
15604
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787031
219
24349
K83
S
I
S
L
E
E
V
K
K
P
R
R
I
I
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.8
58.8
69.9
N.A.
30.4
30.1
N.A.
55.7
31.4
33.5
35.4
N.A.
N.A.
N.A.
N.A.
24.6
Protein Similarity:
100
98.7
67
78.6
N.A.
51.6
49.7
N.A.
67.7
49.7
53.7
55.7
N.A.
N.A.
N.A.
N.A.
41.5
P-Site Identity:
100
93.3
13.3
80
N.A.
46.6
46.6
N.A.
13.3
46.6
46.6
0
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
40
86.6
N.A.
66.6
66.6
N.A.
33.3
66.6
66.6
0
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
19
19
0
0
0
10
0
0
0
0
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
64
% F
% Gly:
0
10
28
0
0
0
0
10
0
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
64
10
% H
% Ile:
0
28
0
0
0
0
0
10
0
0
0
28
73
10
0
% I
% Lys:
0
0
0
37
64
64
37
10
10
28
10
10
0
0
0
% K
% Leu:
0
10
0
19
0
0
0
0
0
0
0
10
0
0
0
% L
% Met:
0
19
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
0
19
0
10
0
10
0
73
10
0
0
0
0
10
% P
% Gln:
10
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
0
0
10
0
0
0
37
73
10
0
0
0
% R
% Ser:
46
0
19
28
0
0
10
0
0
10
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
28
28
0
0
0
0
19
10
10
% T
% Val:
28
19
0
0
0
0
10
37
0
0
0
37
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _