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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM177B
All Species:
16.36
Human Site:
Y37
Identified Species:
36
UniProt:
A6PVY3
Number Species:
10
Phosphosite Substitution
Charge Score:
0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6PVY3
NP_997351.2
158
18145
Y37
D
G
D
I
M
E
E
Y
S
T
E
E
E
E
E
Chimpanzee
Pan troglodytes
XP_001158779
158
18089
Y37
D
G
D
I
M
E
E
Y
S
T
E
E
E
E
E
Rhesus Macaque
Macaca mulatta
XP_001096130
148
17183
D30
K
R
I
I
H
F
V
D
G
D
I
M
E
E
Y
Dog
Lupus familis
XP_536150
173
19823
Y37
D
G
D
V
M
E
E
Y
S
T
E
E
E
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BR63
207
23560
Y64
S
G
E
T
M
E
E
Y
S
T
D
E
D
E
V
Rat
Rattus norvegicus
XP_002729670
209
23751
Y65
S
G
E
T
M
E
E
Y
S
T
D
E
D
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512165
153
17742
A36
P
K
R
I
I
H
F
A
N
G
D
T
M
E
E
Chicken
Gallus gallus
NP_001026373
213
23955
E67
A
S
G
E
T
M
E
E
Y
S
T
D
E
E
E
Frog
Xenopus laevis
NP_001086911
188
21440
E43
A
S
G
E
T
M
E
E
Y
S
T
D
E
E
E
Zebra Danio
Brachydanio rerio
NP_001038926
134
15604
D20
Y
E
C
V
E
L
G
D
L
D
R
K
E
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787031
219
24349
E98
F
S
D
G
V
L
E
E
Y
S
T
D
E
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.8
58.8
69.9
N.A.
30.4
30.1
N.A.
55.7
31.4
33.5
35.4
N.A.
N.A.
N.A.
N.A.
24.6
Protein Similarity:
100
98.7
67
78.6
N.A.
51.6
49.7
N.A.
67.7
49.7
53.7
55.7
N.A.
N.A.
N.A.
N.A.
41.5
P-Site Identity:
100
100
20
86.6
N.A.
60
60
N.A.
20
26.6
26.6
6.6
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
20
100
N.A.
80
80
N.A.
40
40
40
26.6
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
28
0
37
0
0
0
0
19
0
19
28
28
19
0
19
% D
% Glu:
0
10
19
19
10
46
73
28
0
0
28
46
73
91
46
% E
% Phe:
10
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
46
19
10
0
0
10
0
10
10
0
0
0
0
0
% G
% His:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
37
10
0
0
0
0
0
10
0
0
0
10
% I
% Lys:
10
10
0
0
0
0
0
0
0
0
0
10
0
10
0
% K
% Leu:
0
0
0
0
0
19
0
0
10
0
0
0
0
0
0
% L
% Met:
0
0
0
0
46
19
0
0
0
0
0
10
10
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
10
0
0
0
0
0
0
0
10
0
0
0
0
% R
% Ser:
19
28
0
0
0
0
0
0
46
28
0
0
0
0
0
% S
% Thr:
0
0
0
19
19
0
0
0
0
46
28
10
0
0
0
% T
% Val:
0
0
0
19
10
0
10
0
0
0
0
0
0
0
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
46
28
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _