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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DISP2 All Species: 11.21
Human Site: S127 Identified Species: 27.41
UniProt: A7MBM2 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A7MBM2 NP_277045.1 1401 152003 S127 H G S S L S P S P A P S Q R D
Chimpanzee Pan troglodytes XP_523050 1416 154150 S142 H G S S L S P S P A P S Q R D
Rhesus Macaque Macaca mulatta XP_001099799 1523 170630 F147 C L Q P S P S F C L H H P W P
Dog Lupus familis XP_544618 1490 160929 S216 H G S S L S P S P A P S Q R D
Cat Felis silvestris
Mouse Mus musculus Q8CIP5 1345 147926 M119 M P K S Y S H M I A D W P V A
Rat Rattus norvegicus NP_001099453 1522 169333 L145 C R Q P S P S L C L H H P W P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_426392 1437 161874 W117 H E A L E T P W K R W S P G Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6R5J1 1476 164001 C143 S C H T K M Q C H W L H G S H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VNJ5 1218 138960 Y30 V V V S I A V Y C V A C I I V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785823 1428 159059 S179 L R G S E V V S A H P A I G G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.1 34.3 83.8 N.A. 73.5 35.2 N.A. N.A. 54.7 N.A. 42.7 N.A. 23 N.A. N.A. 31.6
Protein Similarity: 100 96.7 52.9 87.1 N.A. 82.3 52.5 N.A. N.A. 69.3 N.A. 57.7 N.A. 38.6 N.A. N.A. 49.1
P-Site Identity: 100 100 0 100 N.A. 20 0 N.A. N.A. 20 N.A. 0 N.A. 6.6 N.A. N.A. 20
P-Site Similarity: 100 100 0 100 N.A. 20 0 N.A. N.A. 33.3 N.A. 6.6 N.A. 20 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 10 0 0 10 40 10 10 0 0 10 % A
% Cys: 20 10 0 0 0 0 0 10 30 0 0 10 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 30 % D
% Glu: 0 10 0 0 20 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % F
% Gly: 0 30 10 0 0 0 0 0 0 0 0 0 10 20 10 % G
% His: 40 0 10 0 0 0 10 0 10 10 20 30 0 0 10 % H
% Ile: 0 0 0 0 10 0 0 0 10 0 0 0 20 10 0 % I
% Lys: 0 0 10 0 10 0 0 0 10 0 0 0 0 0 0 % K
% Leu: 10 10 0 10 30 0 0 10 0 20 10 0 0 0 0 % L
% Met: 10 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 10 0 20 0 20 40 0 30 0 40 0 40 0 20 % P
% Gln: 0 0 20 0 0 0 10 0 0 0 0 0 30 0 10 % Q
% Arg: 0 20 0 0 0 0 0 0 0 10 0 0 0 30 0 % R
% Ser: 10 0 30 60 20 40 20 40 0 0 0 40 0 10 0 % S
% Thr: 0 0 0 10 0 10 0 0 0 0 0 0 0 0 0 % T
% Val: 10 10 10 0 0 10 20 0 0 10 0 0 0 10 10 % V
% Trp: 0 0 0 0 0 0 0 10 0 10 10 10 0 20 0 % W
% Tyr: 0 0 0 0 10 0 0 10 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _