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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DISP2 All Species: 12.12
Human Site: S1306 Identified Species: 29.63
UniProt: A7MBM2 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A7MBM2 NP_277045.1 1401 152003 S1306 C L S T S E P S A R V P D S V
Chimpanzee Pan troglodytes XP_523050 1416 154150 S1321 C L S T S E P S A R V P D S V
Rhesus Macaque Macaca mulatta XP_001099799 1523 170630 I1328 A E G F V H P I T H I H H C P
Dog Lupus familis XP_544618 1490 160929 S1395 C L S T S E P S A R V P D S V
Cat Felis silvestris
Mouse Mus musculus Q8CIP5 1345 147926 R1252 C A S E H S V R V P D S V G T
Rat Rattus norvegicus NP_001099453 1522 169333 T1417 D T E G S G G T E T K V C G L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_426392 1437 161874 T1299 A Q Q Q S D Y T S D N S H L P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6R5J1 1476 164001 K1373 S M D D H I H K R L L S C Q S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VNJ5 1218 138960 P1125 G F L E L K W P L W S K R S S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785823 1428 159059 T1333 G Y C S H M S T N R G S S Y C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.1 34.3 83.8 N.A. 73.5 35.2 N.A. N.A. 54.7 N.A. 42.7 N.A. 23 N.A. N.A. 31.6
Protein Similarity: 100 96.7 52.9 87.1 N.A. 82.3 52.5 N.A. N.A. 69.3 N.A. 57.7 N.A. 38.6 N.A. N.A. 49.1
P-Site Identity: 100 100 6.6 100 N.A. 13.3 6.6 N.A. N.A. 6.6 N.A. 0 N.A. 6.6 N.A. N.A. 6.6
P-Site Similarity: 100 100 13.3 100 N.A. 13.3 20 N.A. N.A. 26.6 N.A. 13.3 N.A. 13.3 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 10 0 0 0 0 0 0 30 0 0 0 0 0 0 % A
% Cys: 40 0 10 0 0 0 0 0 0 0 0 0 20 10 10 % C
% Asp: 10 0 10 10 0 10 0 0 0 10 10 0 30 0 0 % D
% Glu: 0 10 10 20 0 30 0 0 10 0 0 0 0 0 0 % E
% Phe: 0 10 0 10 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 20 0 10 10 0 10 10 0 0 0 10 0 0 20 0 % G
% His: 0 0 0 0 30 10 10 0 0 10 0 10 20 0 0 % H
% Ile: 0 0 0 0 0 10 0 10 0 0 10 0 0 0 0 % I
% Lys: 0 0 0 0 0 10 0 10 0 0 10 10 0 0 0 % K
% Leu: 0 30 10 0 10 0 0 0 10 10 10 0 0 10 10 % L
% Met: 0 10 0 0 0 10 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 10 0 10 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 40 10 0 10 0 30 0 0 20 % P
% Gln: 0 10 10 10 0 0 0 0 0 0 0 0 0 10 0 % Q
% Arg: 0 0 0 0 0 0 0 10 10 40 0 0 10 0 0 % R
% Ser: 10 0 40 10 50 10 10 30 10 0 10 40 10 40 20 % S
% Thr: 0 10 0 30 0 0 0 30 10 10 0 0 0 0 10 % T
% Val: 0 0 0 0 10 0 10 0 10 0 30 10 10 0 30 % V
% Trp: 0 0 0 0 0 0 10 0 0 10 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 10 0 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _