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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DISP2 All Species: 14.55
Human Site: S1393 Identified Species: 35.56
UniProt: A7MBM2 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A7MBM2 NP_277045.1 1401 152003 S1393 D V W L R R P S T H T S G Y S
Chimpanzee Pan troglodytes XP_523050 1416 154150 S1408 D V W L R R P S T H T S G Y S
Rhesus Macaque Macaca mulatta XP_001099799 1523 170630 L1513 A V L I H S E L S G E S L L I
Dog Lupus familis XP_544618 1490 160929 S1482 D V W L R R P S T H T S G Y S
Cat Felis silvestris
Mouse Mus musculus Q8CIP5 1345 147926 T1338 V W L R R P S T Y T S G Y S S
Rat Rattus norvegicus NP_001099453 1522 169333 S1512 T H S D L S V S G E S L L I K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_426392 1437 161874 S1429 D V W I K R S S A Q S S G Y N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6R5J1 1476 164001 E1469 P D V W I K R E G K G E G G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VNJ5 1218 138960 Q1211 T M H E C K Y Q T Y P S T S N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785823 1428 159059 G1421 R V R L C Y T G M S P L T Q D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.1 34.3 83.8 N.A. 73.5 35.2 N.A. N.A. 54.7 N.A. 42.7 N.A. 23 N.A. N.A. 31.6
Protein Similarity: 100 96.7 52.9 87.1 N.A. 82.3 52.5 N.A. N.A. 69.3 N.A. 57.7 N.A. 38.6 N.A. N.A. 49.1
P-Site Identity: 100 100 13.3 100 N.A. 13.3 6.6 N.A. N.A. 53.3 N.A. 13.3 N.A. 13.3 N.A. N.A. 13.3
P-Site Similarity: 100 100 26.6 100 N.A. 26.6 13.3 N.A. N.A. 80 N.A. 20 N.A. 40 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 20 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 40 10 0 10 0 0 0 0 0 0 0 0 0 0 10 % D
% Glu: 0 0 0 10 0 0 10 10 0 10 10 10 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 10 20 10 10 10 50 10 0 % G
% His: 0 10 10 0 10 0 0 0 0 30 0 0 0 0 0 % H
% Ile: 0 0 0 20 10 0 0 0 0 0 0 0 0 10 10 % I
% Lys: 0 0 0 0 10 20 0 0 0 10 0 0 0 0 10 % K
% Leu: 0 0 20 40 10 0 0 10 0 0 0 20 20 10 0 % L
% Met: 0 10 0 0 0 0 0 0 10 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20 % N
% Pro: 10 0 0 0 0 10 30 0 0 0 20 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 10 0 10 0 0 0 10 0 % Q
% Arg: 10 0 10 10 40 40 10 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 10 0 0 20 20 50 10 10 30 60 0 20 50 % S
% Thr: 20 0 0 0 0 0 10 10 40 10 30 0 20 0 0 % T
% Val: 10 60 10 0 0 0 10 0 0 0 0 0 0 0 0 % V
% Trp: 0 10 40 10 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 10 0 10 10 0 0 10 40 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _