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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBKBP1 All Species: 24.85
Human Site: S142 Identified Species: 68.33
UniProt: A7MCY6 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A7MCY6 NP_055541.1 615 67702 S142 E K L C V E K S D L E T E L R
Chimpanzee Pan troglodytes XP_511928 588 64815 S142 E K L C V E K S D L E T E L R
Rhesus Macaque Macaca mulatta XP_001082242 615 67718 S142 E K L C V E K S D L E T E L G
Dog Lupus familis XP_548163 691 75076 S228 E K L C V E K S D L E T E L G
Cat Felis silvestris
Mouse Mus musculus A2A9T0 611 66983 S142 E K L C V E K S D L E T E L G
Rat Rattus norvegicus Q6DG50 613 67136 S142 E K L C V E K S D L E T E L G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505916 222 23523
Chicken Gallus gallus Q5ZMJ9 888 100785 R268 E R N S K K E R E K E K E K T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001919320 632 71433 S143 E K I H M E K S S L Q R D L D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.7 98.3 81.7 N.A. 93.1 93.5 N.A. 27.1 20.9 N.A. 43.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 89.2 98.6 83.9 N.A. 94.9 94.9 N.A. 30.2 32.7 N.A. 57.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 93.3 N.A. 93.3 93.3 N.A. 0 20 N.A. 46.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 93.3 N.A. 93.3 93.3 N.A. 0 46.6 N.A. 73.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 67 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 67 0 0 0 12 0 12 % D
% Glu: 89 0 0 0 0 78 12 0 12 0 78 0 78 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 45 % G
% His: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 78 0 0 12 12 78 0 0 12 0 12 0 12 0 % K
% Leu: 0 0 67 0 0 0 0 0 0 78 0 0 0 78 0 % L
% Met: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % Q
% Arg: 0 12 0 0 0 0 0 12 0 0 0 12 0 0 23 % R
% Ser: 0 0 0 12 0 0 0 78 12 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 67 0 0 12 % T
% Val: 0 0 0 0 67 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _