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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POM121C All Species: 5.15
Human Site: T540 Identified Species: 14.17
UniProt: A8CG34 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A8CG34 NP_001092885 1229 125059 T540 D A A S N S V T E T P P T T Q
Chimpanzee Pan troglodytes XP_001144107 1228 125027 S548 T P P I T Q P S F T F T L P A
Rhesus Macaque Macaca mulatta XP_001110260 1225 124873 T536 D A A S N S V T E T P P T T Q
Dog Lupus familis XP_546930 890 89245 G212 A A D K E A Q G E K A A D T T
Cat Felis silvestris
Mouse Mus musculus Q8K3Z9 1200 121003 A517 D L D M E R K A S L Q W F N K
Rat Rattus norvegicus P52591 1199 120766 A517 D L D M E R R A S L Q W F N K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514514 686 70317 R8 D H L A S Q N R L A L S P R R
Chicken Gallus gallus XP_415711 809 79517 P131 K R G S L S P P S A S G S S G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_696713 1201 123069 K514 V K D L D M E K K A A L S K I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.2 93.8 55.2 N.A. 68 69.1 N.A. 32.2 32.7 N.A. 32.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 95.9 95.5 61 N.A. 76.3 77.3 N.A. 40.4 42 N.A. 47.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 100 20 N.A. 6.6 6.6 N.A. 6.6 13.3 N.A. 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 13.3 100 26.6 N.A. 13.3 13.3 N.A. 26.6 26.6 N.A. 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 34 23 12 0 12 0 23 0 34 23 12 0 0 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 56 0 45 0 12 0 0 0 0 0 0 0 12 0 0 % D
% Glu: 0 0 0 0 34 0 12 0 34 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 12 0 12 0 23 0 0 % F
% Gly: 0 0 12 0 0 0 0 12 0 0 0 12 0 0 12 % G
% His: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 12 % I
% Lys: 12 12 0 12 0 0 12 12 12 12 0 0 0 12 23 % K
% Leu: 0 23 12 12 12 0 0 0 12 23 12 12 12 0 0 % L
% Met: 0 0 0 23 0 12 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 23 0 12 0 0 0 0 0 0 23 0 % N
% Pro: 0 12 12 0 0 0 23 12 0 0 23 23 12 12 0 % P
% Gln: 0 0 0 0 0 23 12 0 0 0 23 0 0 0 23 % Q
% Arg: 0 12 0 0 0 23 12 12 0 0 0 0 0 12 12 % R
% Ser: 0 0 0 34 12 34 0 12 34 0 12 12 23 12 0 % S
% Thr: 12 0 0 0 12 0 0 23 0 34 0 12 23 34 12 % T
% Val: 12 0 0 0 0 0 23 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 23 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _