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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEIS3P2
All Species:
14.24
Human Site:
S178
Identified Species:
34.81
UniProt:
A8K0S8
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A8K0S8
NP_001009813
358
39220
S178
D
Y
P
A
S
C
L
S
L
P
D
Q
N
N
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_541536
393
42963
S207
D
Y
P
P
S
C
P
S
L
P
D
Q
N
N
A
Cat
Felis silvestris
Mouse
Mus musculus
P97368
378
41738
S198
D
Y
T
A
S
C
P
S
L
P
D
Q
N
T
T
Rat
Rattus norvegicus
NP_001101942
378
41597
S198
D
Y
A
A
S
C
P
S
L
P
D
Q
N
T
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q7ZY13
451
48950
S201
D
F
T
G
S
C
T
S
L
S
D
Q
N
N
T
Zebra Danio
Brachydanio rerio
NP_570985
393
43026
L211
L
S
G
S
S
T
N
L
A
D
H
N
P
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O46339
487
52766
K197
H
R
Y
I
S
C
L
K
G
K
M
P
I
D
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N5D6
564
60870
P260
P
Y
E
P
Q
S
V
P
L
P
E
N
A
G
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q1PFD1
290
33005
Y129
G
E
G
S
S
K
V
Y
T
G
L
A
L
Q
A
Baker's Yeast
Sacchar. cerevisiae
P53147
276
31239
G115
R
N
Y
I
I
T
V
G
G
P
P
V
T
S
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
78.3
N.A.
80.9
82
N.A.
N.A.
N.A.
56.9
60.3
N.A.
41.8
N.A.
30.6
N.A.
Protein Similarity:
100
N.A.
N.A.
81.6
N.A.
84.6
85.7
N.A.
N.A.
N.A.
64.7
72.2
N.A.
52.7
N.A.
43.2
N.A.
P-Site Identity:
100
N.A.
N.A.
80
N.A.
73.3
73.3
N.A.
N.A.
N.A.
60
6.6
N.A.
20
N.A.
20
N.A.
P-Site Similarity:
100
N.A.
N.A.
80
N.A.
73.3
73.3
N.A.
N.A.
N.A.
66.6
13.3
N.A.
33.3
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.4
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.8
37.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
30
0
0
0
0
10
0
0
10
10
10
20
% A
% Cys:
0
0
0
0
0
60
0
0
0
0
0
0
0
0
0
% C
% Asp:
50
0
0
0
0
0
0
0
0
10
50
0
0
10
0
% D
% Glu:
0
10
10
0
0
0
0
0
0
0
10
0
0
0
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
20
10
0
0
0
10
20
10
0
0
0
10
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
20
10
0
0
0
0
0
0
0
10
0
10
% I
% Lys:
0
0
0
0
0
10
0
10
0
10
0
0
0
0
0
% K
% Leu:
10
0
0
0
0
0
20
10
60
0
10
0
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
10
0
0
0
0
20
50
30
0
% N
% Pro:
10
0
20
20
0
0
30
10
0
60
10
10
10
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
0
50
0
10
0
% Q
% Arg:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
0
20
80
10
0
50
0
10
0
0
0
10
20
% S
% Thr:
0
0
20
0
0
20
10
0
10
0
0
0
10
20
30
% T
% Val:
0
0
0
0
0
0
30
0
0
0
0
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
50
20
0
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _