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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WASH1
All Species:
10.91
Human Site:
S165
Identified Species:
20
UniProt:
A8K0Z3
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A8K0Z3
NP_878908.3
465
50328
S165
E
G
L
G
G
L
P
S
N
I
S
S
V
S
S
Chimpanzee
Pan troglodytes
XP_001145900
468
50425
S165
E
G
L
G
G
L
P
S
N
I
S
S
V
S
S
Rhesus Macaque
Macaca mulatta
XP_001094494
443
47510
N153
V
S
S
L
L
L
F
N
T
T
E
N
L
Y
K
Dog
Lupus familis
XP_543873
471
51116
S165
E
G
L
G
G
L
P
S
N
I
S
S
V
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8VDD8
475
51640
P164
E
E
G
L
G
G
L
P
S
N
I
S
S
I
S
Rat
Rattus norvegicus
B2RYF7
475
51309
P164
E
E
G
L
G
G
L
P
S
N
I
S
S
I
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517605
495
52719
G180
E
G
L
G
S
L
P
G
N
I
S
S
L
S
S
Chicken
Gallus gallus
Q5ZKA6
476
51664
R165
E
G
L
G
S
L
P
R
N
I
S
S
L
S
S
Frog
Xenopus laevis
Q5U4A3
472
51105
R162
E
G
L
G
S
L
P
R
N
I
N
S
V
S
S
Zebra Danio
Brachydanio rerio
A4IG59
481
52093
R165
E
G
L
G
S
L
P
R
N
V
N
S
V
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7JW27
499
53192
S176
L
P
A
G
G
V
R
S
V
P
S
L
M
R
F
Honey Bee
Apis mellifera
XP_001120697
464
51758
E160
V
R
S
K
S
N
K
E
V
Y
T
D
N
E
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785243
480
51242
L156
T
W
E
G
L
G
G
L
P
R
N
V
G
S
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.3
87.3
88.3
N.A.
82.3
82.1
N.A.
75.1
76.2
67.8
65.4
N.A.
29.8
25.8
N.A.
45.8
Protein Similarity:
100
97.2
89.8
92.1
N.A.
89
88
N.A.
82.2
84.2
78.3
76.5
N.A.
44.4
46.4
N.A.
62.7
P-Site Identity:
100
100
6.6
100
N.A.
26.6
26.6
N.A.
80
80
80
73.3
N.A.
26.6
0
N.A.
13.3
P-Site Similarity:
100
100
26.6
100
N.A.
33.3
33.3
N.A.
86.6
86.6
86.6
86.6
N.A.
40
6.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% D
% Glu:
70
16
8
0
0
0
0
8
0
0
8
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% F
% Gly:
0
54
16
70
47
24
8
8
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
47
16
0
0
16
8
% I
% Lys:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
8
% K
% Leu:
8
0
54
24
16
62
16
8
0
0
0
8
24
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% M
% Asn:
0
0
0
0
0
8
0
8
54
16
24
8
8
0
0
% N
% Pro:
0
8
0
0
0
0
54
16
8
8
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
0
0
8
24
0
8
0
0
0
8
0
% R
% Ser:
0
8
16
0
39
0
0
31
16
0
47
70
16
62
70
% S
% Thr:
8
0
0
0
0
0
0
0
8
8
8
0
0
0
0
% T
% Val:
16
0
0
0
0
8
0
0
16
8
0
8
39
0
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _