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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
A2ML1
All Species:
8.18
Human Site:
S1174
Identified Species:
22.5
UniProt:
A8K2U0
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A8K2U0
NP_653271
1454
161104
S1174
S
G
E
S
I
Y
W
S
Q
K
P
T
P
S
S
Chimpanzee
Pan troglodytes
XP_520828
1454
161059
S1174
S
G
E
S
I
H
W
S
Q
K
P
T
P
S
S
Rhesus Macaque
Macaca mulatta
XP_001114289
1468
163174
K1182
V
H
W
E
R
P
Q
K
P
K
A
P
V
G
H
Dog
Lupus familis
XP_543824
1449
160598
S1169
S
G
G
S
I
H
W
S
Q
K
P
I
P
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6GQT1
1474
164308
K1188
V
H
W
T
R
A
Q
K
P
R
V
P
A
D
L
Rat
Rattus norvegicus
P06238
1472
163767
K1186
V
H
W
T
R
P
Q
K
P
S
V
S
V
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P20740
1473
166336
Q1186
D
G
S
K
Y
W
E
Q
N
Q
R
S
A
P
E
Frog
Xenopus laevis
NP_001128549
1474
163608
H1186
V
K
S
E
G
Q
L
H
W
E
R
K
P
A
A
Zebra Danio
Brachydanio rerio
XP_001920744
1521
168785
E1241
L
D
N
Q
A
R
R
E
G
A
G
R
Y
W
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
40.4
80.7
N.A.
39.4
39.6
N.A.
N.A.
37.7
44.7
39.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
59.4
89
N.A.
58
58.9
N.A.
N.A.
56.9
62.4
56.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
6.6
73.3
N.A.
0
0
N.A.
N.A.
6.6
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
6.6
80
N.A.
13.3
20
N.A.
N.A.
26.6
26.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
12
0
0
0
12
12
0
23
23
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
12
0
0
0
0
0
0
0
0
0
0
0
12
0
% D
% Glu:
0
0
23
23
0
0
12
12
0
12
0
0
0
0
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
45
12
0
12
0
0
0
12
0
12
0
0
12
0
% G
% His:
0
34
0
0
0
23
0
12
0
0
0
0
0
0
12
% H
% Ile:
0
0
0
0
34
0
0
0
0
0
0
12
0
0
0
% I
% Lys:
0
12
0
12
0
0
0
34
0
45
0
12
0
0
0
% K
% Leu:
12
0
0
0
0
0
12
0
0
0
0
0
0
0
34
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
12
0
0
0
0
0
12
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
23
0
0
34
0
34
23
45
12
0
% P
% Gln:
0
0
0
12
0
12
34
12
34
12
0
0
0
0
0
% Q
% Arg:
0
0
0
0
34
12
12
0
0
12
23
12
0
0
0
% R
% Ser:
34
0
23
34
0
0
0
34
0
12
0
23
0
34
34
% S
% Thr:
0
0
0
23
0
0
0
0
0
0
0
23
0
0
0
% T
% Val:
45
0
0
0
0
0
0
0
0
0
23
0
23
0
0
% V
% Trp:
0
0
34
0
0
12
34
0
12
0
0
0
0
12
0
% W
% Tyr:
0
0
0
0
12
12
0
0
0
0
0
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _