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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: A2ML1 All Species: 5.45
Human Site: T402 Identified Species: 15
UniProt: A8K2U0 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A8K2U0 NP_653271 1454 161104 T402 N N G L A P F T L E T S G W N
Chimpanzee Pan troglodytes XP_520828 1454 161059 T402 N N G L A P F T L E T S G W N
Rhesus Macaque Macaca mulatta XP_001114289 1468 163174 N394 G L V Q F S I N T T N V M G T
Dog Lupus familis XP_543824 1449 160598 K413 N D G L A P F K L D T V N W N
Cat Felis silvestris
Mouse Mus musculus Q6GQT1 1474 164308 N416 G L A R F S I N T D D I M G T
Rat Rattus norvegicus P06238 1472 163767 N413 G L A R F S I N T D D I M G T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P20740 1473 166336 T418 I A P F S I D T S K I F D P E
Frog Xenopus laevis NP_001128549 1474 163608 D401 G L A P F K L D N T A D W K A
Zebra Danio Brachydanio rerio XP_001920744 1521 168785 F443 R E Y I N V Y F E D T P D T Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 40.4 80.7 N.A. 39.4 39.6 N.A. N.A. 37.7 44.7 39.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.5 59.4 89 N.A. 58 58.9 N.A. N.A. 56.9 62.4 56.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 0 66.6 N.A. 0 0 N.A. N.A. 6.6 0 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 0 80 N.A. 6.6 6.6 N.A. N.A. 20 0 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 34 0 34 0 0 0 0 0 12 0 0 0 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 12 0 0 0 0 12 12 0 45 23 12 23 0 0 % D
% Glu: 0 12 0 0 0 0 0 0 12 23 0 0 0 0 12 % E
% Phe: 0 0 0 12 45 0 34 12 0 0 0 12 0 0 0 % F
% Gly: 45 0 34 0 0 0 0 0 0 0 0 0 23 34 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 12 0 0 12 0 12 34 0 0 0 12 23 0 0 0 % I
% Lys: 0 0 0 0 0 12 0 12 0 12 0 0 0 12 0 % K
% Leu: 0 45 0 34 0 0 12 0 34 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 34 0 0 % M
% Asn: 34 23 0 0 12 0 0 34 12 0 12 0 12 0 34 % N
% Pro: 0 0 12 12 0 34 0 0 0 0 0 12 0 12 0 % P
% Gln: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 12 0 0 23 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 12 34 0 0 12 0 0 23 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 34 34 23 45 0 0 12 34 % T
% Val: 0 0 12 0 0 12 0 0 0 0 0 23 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 12 34 0 % W
% Tyr: 0 0 12 0 0 0 12 0 0 0 0 0 0 0 12 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _