KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EFCAB7
All Species:
27.88
Human Site:
S570
Identified Species:
76.67
UniProt:
A8K855
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A8K855
NP_115813.2
629
71981
S570
T
S
V
I
E
N
K
S
D
E
K
V
I
I
H
Chimpanzee
Pan troglodytes
XP_513455
629
72088
S570
T
S
V
I
E
N
K
S
D
E
K
V
I
I
H
Rhesus Macaque
Macaca mulatta
XP_001087522
629
72103
S570
T
S
V
I
E
N
K
S
D
E
K
V
I
I
H
Dog
Lupus familis
XP_536685
631
72413
S572
T
S
V
I
E
N
K
S
D
N
K
V
I
I
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8VDY4
628
71424
S569
T
S
I
I
E
N
K
S
D
N
K
V
I
I
H
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517608
719
81339
S660
S
S
V
I
E
N
K
S
D
T
K
V
I
I
Y
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6DCF6
620
70792
S561
T
S
V
M
E
N
K
S
D
E
K
L
I
L
Q
Zebra Danio
Brachydanio rerio
NP_001002120
603
68184
S551
Q
K
V
T
V
H
I
S
N
E
Q
S
K
N
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789667
719
80712
G659
T
F
V
M
E
N
T
G
S
K
K
C
G
M
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
96.9
89.2
N.A.
82.8
N.A.
N.A.
67.3
N.A.
61.6
54.2
N.A.
N.A.
N.A.
N.A.
32.6
Protein Similarity:
100
99.3
98.5
94.7
N.A.
91.4
N.A.
N.A.
76.7
N.A.
77.7
69.9
N.A.
N.A.
N.A.
N.A.
50
P-Site Identity:
100
100
100
93.3
N.A.
86.6
N.A.
N.A.
80
N.A.
73.3
20
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
N.A.
N.A.
93.3
N.A.
93.3
40
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
78
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
89
0
0
0
0
56
0
0
0
0
0
% E
% Phe:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
12
% F
% Gly:
0
0
0
0
0
0
0
12
0
0
0
0
12
0
0
% G
% His:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
56
% H
% Ile:
0
0
12
67
0
0
12
0
0
0
0
0
78
67
0
% I
% Lys:
0
12
0
0
0
0
78
0
0
12
89
0
12
0
12
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
12
0
12
0
% L
% Met:
0
0
0
23
0
0
0
0
0
0
0
0
0
12
0
% M
% Asn:
0
0
0
0
0
89
0
0
12
23
0
0
0
12
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
12
0
0
0
0
0
0
0
0
0
12
0
0
0
12
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
12
78
0
0
0
0
0
89
12
0
0
12
0
0
0
% S
% Thr:
78
0
0
12
0
0
12
0
0
12
0
0
0
0
0
% T
% Val:
0
0
89
0
12
0
0
0
0
0
0
67
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _