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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EFCAB7
All Species:
16.06
Human Site:
T250
Identified Species:
44.17
UniProt:
A8K855
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A8K855
NP_115813.2
629
71981
T250
T
S
V
S
F
T
V
T
M
G
A
N
G
N
R
Chimpanzee
Pan troglodytes
XP_513455
629
72088
T250
T
S
V
S
F
T
V
T
M
G
P
N
G
N
R
Rhesus Macaque
Macaca mulatta
XP_001087522
629
72103
T250
T
S
V
S
F
T
I
T
M
G
A
N
G
N
R
Dog
Lupus familis
XP_536685
631
72413
T252
T
S
V
S
C
T
I
T
M
D
V
N
S
N
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8VDY4
628
71424
T250
T
S
V
S
F
T
M
T
M
S
A
N
S
N
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517608
719
81339
I339
K
A
S
V
S
C
S
I
I
M
G
A
R
S
T
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6DCF6
620
70792
N243
A
T
M
S
T
V
I
N
M
G
I
P
G
T
R
Zebra Danio
Brachydanio rerio
NP_001002120
603
68184
M247
Q
D
W
H
H
T
F
M
R
G
C
F
Y
M
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789667
719
80712
E301
E
S
S
L
K
R
L
E
R
K
E
R
K
Q
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
96.9
89.2
N.A.
82.8
N.A.
N.A.
67.3
N.A.
61.6
54.2
N.A.
N.A.
N.A.
N.A.
32.6
Protein Similarity:
100
99.3
98.5
94.7
N.A.
91.4
N.A.
N.A.
76.7
N.A.
77.7
69.9
N.A.
N.A.
N.A.
N.A.
50
P-Site Identity:
100
93.3
93.3
66.6
N.A.
73.3
N.A.
N.A.
0
N.A.
33.3
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
93.3
100
73.3
N.A.
86.6
N.A.
N.A.
20
N.A.
53.3
13.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
12
0
0
0
0
0
0
0
0
34
12
0
0
0
% A
% Cys:
0
0
0
0
12
12
0
0
0
0
12
0
0
0
0
% C
% Asp:
0
12
0
0
0
0
0
0
0
12
0
0
0
0
0
% D
% Glu:
12
0
0
0
0
0
0
12
0
0
12
0
0
0
12
% E
% Phe:
0
0
0
0
45
0
12
0
0
0
0
12
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
56
12
0
45
0
0
% G
% His:
0
0
0
12
12
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
34
12
12
0
12
0
0
0
0
% I
% Lys:
12
0
0
0
12
0
0
0
0
12
0
0
12
0
12
% K
% Leu:
0
0
0
12
0
0
12
0
0
0
0
0
0
0
0
% L
% Met:
0
0
12
0
0
0
12
12
67
12
0
0
0
12
0
% M
% Asn:
0
0
0
0
0
0
0
12
0
0
0
56
0
56
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
12
12
0
0
0
% P
% Gln:
12
0
0
0
0
0
0
0
0
0
0
0
0
12
12
% Q
% Arg:
0
0
0
0
0
12
0
0
23
0
0
12
12
0
56
% R
% Ser:
0
67
23
67
12
0
12
0
0
12
0
0
23
12
0
% S
% Thr:
56
12
0
0
12
67
0
56
0
0
0
0
0
12
12
% T
% Val:
0
0
56
12
0
12
23
0
0
0
12
0
0
0
0
% V
% Trp:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _