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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EFCAB7
All Species:
17.58
Human Site:
T395
Identified Species:
48.33
UniProt:
A8K855
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A8K855
NP_115813.2
629
71981
T395
Q
L
V
Y
R
D
E
T
G
E
L
F
L
T
K
Chimpanzee
Pan troglodytes
XP_513455
629
72088
T395
Q
L
V
Y
R
D
E
T
G
E
L
F
L
T
K
Rhesus Macaque
Macaca mulatta
XP_001087522
629
72103
T395
Q
L
V
Y
R
D
Q
T
G
K
L
F
L
T
K
Dog
Lupus familis
XP_536685
631
72413
T397
Q
L
V
Y
R
D
E
T
G
E
L
F
L
T
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8VDY4
628
71424
T394
Q
L
V
H
R
D
E
T
G
E
L
S
L
T
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517608
719
81339
K485
K
L
V
F
R
G
E
K
G
E
L
S
L
T
K
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6DCF6
620
70792
D388
V
Y
R
D
G
N
E
D
L
V
L
T
P
E
F
Zebra Danio
Brachydanio rerio
NP_001002120
603
68184
G391
F
E
V
I
D
L
D
G
S
G
L
L
S
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789667
719
80712
D473
K
L
I
Q
P
K
G
D
E
E
C
E
L
T
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
96.9
89.2
N.A.
82.8
N.A.
N.A.
67.3
N.A.
61.6
54.2
N.A.
N.A.
N.A.
N.A.
32.6
Protein Similarity:
100
99.3
98.5
94.7
N.A.
91.4
N.A.
N.A.
76.7
N.A.
77.7
69.9
N.A.
N.A.
N.A.
N.A.
50
P-Site Identity:
100
100
86.6
100
N.A.
80
N.A.
N.A.
66.6
N.A.
13.3
13.3
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
100
100
100
100
N.A.
86.6
N.A.
N.A.
80
N.A.
20
26.6
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% C
% Asp:
0
0
0
12
12
56
12
23
0
0
0
0
0
0
0
% D
% Glu:
0
12
0
0
0
0
67
0
12
67
0
12
0
12
12
% E
% Phe:
12
0
0
12
0
0
0
0
0
0
0
45
0
0
12
% F
% Gly:
0
0
0
0
12
12
12
12
67
12
0
0
0
0
0
% G
% His:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
12
12
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
23
0
0
0
0
12
0
12
0
12
0
0
0
0
67
% K
% Leu:
0
78
0
0
0
12
0
0
12
0
89
12
78
12
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
12
0
0
0
0
0
0
0
12
0
0
% P
% Gln:
56
0
0
12
0
0
12
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
12
0
67
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
12
0
0
23
12
0
12
% S
% Thr:
0
0
0
0
0
0
0
56
0
0
0
12
0
78
0
% T
% Val:
12
0
78
0
0
0
0
0
0
12
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
0
45
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _