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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EFCAB7
All Species:
24.55
Human Site:
Y43
Identified Species:
67.5
UniProt:
A8K855
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A8K855
NP_115813.2
629
71981
Y43
Y
M
N
C
R
A
A
Y
L
T
V
F
K
S
S
Chimpanzee
Pan troglodytes
XP_513455
629
72088
Y43
Y
M
N
C
R
A
A
Y
L
T
V
F
K
S
S
Rhesus Macaque
Macaca mulatta
XP_001087522
629
72103
Y43
Y
M
N
C
R
A
A
Y
L
T
V
F
K
S
S
Dog
Lupus familis
XP_536685
631
72413
Y45
Y
M
N
C
R
A
A
Y
L
T
V
F
K
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8VDY4
628
71424
Y43
Y
M
N
C
R
A
A
Y
L
T
I
F
K
S
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517608
719
81339
Y132
Y
L
N
C
R
A
A
Y
L
S
V
F
K
S
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6DCF6
620
70792
K44
A
A
Y
L
T
V
F
K
S
S
L
D
N
I
T
Zebra Danio
Brachydanio rerio
NP_001002120
603
68184
R43
T
V
L
Q
Q
A
G
R
N
P
S
Q
K
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789667
719
80712
Y66
T
A
E
I
K
A
A
Y
I
A
V
L
N
H
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
96.9
89.2
N.A.
82.8
N.A.
N.A.
67.3
N.A.
61.6
54.2
N.A.
N.A.
N.A.
N.A.
32.6
Protein Similarity:
100
99.3
98.5
94.7
N.A.
91.4
N.A.
N.A.
76.7
N.A.
77.7
69.9
N.A.
N.A.
N.A.
N.A.
50
P-Site Identity:
100
100
100
100
N.A.
93.3
N.A.
N.A.
86.6
N.A.
0
13.3
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
N.A.
20
33.3
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
23
0
0
0
89
78
0
0
12
0
0
0
12
0
% A
% Cys:
0
0
0
67
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% D
% Glu:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
12
0
0
0
0
67
0
0
0
% F
% Gly:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% H
% Ile:
0
0
0
12
0
0
0
0
12
0
12
0
0
12
12
% I
% Lys:
0
0
0
0
12
0
0
12
0
0
0
0
78
0
0
% K
% Leu:
0
12
12
12
0
0
0
0
67
0
12
12
0
0
12
% L
% Met:
0
56
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
67
0
0
0
0
0
12
0
0
0
23
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% P
% Gln:
0
0
0
12
12
0
0
0
0
0
0
12
0
0
0
% Q
% Arg:
0
0
0
0
67
0
0
12
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
12
23
12
0
0
67
67
% S
% Thr:
23
0
0
0
12
0
0
0
0
56
0
0
0
0
12
% T
% Val:
0
12
0
0
0
12
0
0
0
0
67
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
67
0
12
0
0
0
0
78
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _