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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SFI1 All Species: 9.39
Human Site: S1142 Identified Species: 29.52
UniProt: A8K8P3 Number Species: 7
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A8K8P3 NP_001007468.1 1242 147664 S1142 T R A G P G L S T A G S L D L
Chimpanzee Pan troglodytes XP_001148312 1241 147419 S1141 T R A G P G L S T A G S L D L
Rhesus Macaque Macaca mulatta XP_001111164 1219 144812 S1119 T R A G P G L S T T G S L D L
Dog Lupus familis XP_852846 1254 149341 M1149 T G R S S G T M A C S P I T A
Cat Felis silvestris
Mouse Mus musculus Q3UZY0 1216 144015 S1115 R T E P V Y G S E A T G H T E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517622 1137 134753 F1089 G F S G Q E K F T A S P V S T
Chicken Gallus gallus XP_425281 812 97208 K770 Q H Q D S I Q K V Q K E L D Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780221 945 112945 I903 S E V T L P L I T Q R S S M L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 90.4 73 N.A. 63.2 N.A. N.A. 40.5 21 N.A. N.A. N.A. N.A. N.A. N.A. 21.3
Protein Similarity: 100 99 93.4 81.8 N.A. 73.8 N.A. N.A. 56.9 34.1 N.A. N.A. N.A. N.A. N.A. N.A. 35.9
P-Site Identity: 100 100 93.3 13.3 N.A. 13.3 N.A. N.A. 20 13.3 N.A. N.A. N.A. N.A. N.A. N.A. 26.6
P-Site Similarity: 100 100 93.3 20 N.A. 13.3 N.A. N.A. 33.3 13.3 N.A. N.A. N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 38 0 0 0 0 0 13 50 0 0 0 0 13 % A
% Cys: 0 0 0 0 0 0 0 0 0 13 0 0 0 0 0 % C
% Asp: 0 0 0 13 0 0 0 0 0 0 0 0 0 50 0 % D
% Glu: 0 13 13 0 0 13 0 0 13 0 0 13 0 0 13 % E
% Phe: 0 13 0 0 0 0 0 13 0 0 0 0 0 0 0 % F
% Gly: 13 13 0 50 0 50 13 0 0 0 38 13 0 0 0 % G
% His: 0 13 0 0 0 0 0 0 0 0 0 0 13 0 0 % H
% Ile: 0 0 0 0 0 13 0 13 0 0 0 0 13 0 0 % I
% Lys: 0 0 0 0 0 0 13 13 0 0 13 0 0 0 0 % K
% Leu: 0 0 0 0 13 0 50 0 0 0 0 0 50 0 50 % L
% Met: 0 0 0 0 0 0 0 13 0 0 0 0 0 13 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 13 38 13 0 0 0 0 0 25 0 0 0 % P
% Gln: 13 0 13 0 13 0 13 0 0 25 0 0 0 0 13 % Q
% Arg: 13 38 13 0 0 0 0 0 0 0 13 0 0 0 0 % R
% Ser: 13 0 13 13 25 0 0 50 0 0 25 50 13 13 0 % S
% Thr: 50 13 0 13 0 0 13 0 63 13 13 0 0 25 13 % T
% Val: 0 0 13 0 13 0 0 0 13 0 0 0 13 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _