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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SFI1 All Species: 12.12
Human Site: S335 Identified Species: 38.1
UniProt: A8K8P3 Number Species: 7
    Phosphosite Substitution
    Charge Score: -0.43
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A8K8P3 NP_001007468.1 1242 147664 S335 Q A W E R R E S L Y A H H A Q
Chimpanzee Pan troglodytes XP_001148312 1241 147419 S334 Q A W E R R E S L Y A H H A Q
Rhesus Macaque Macaca mulatta XP_001111164 1219 144812 S312 Q A W E Q R Q S L Y A Y H A Q
Dog Lupus familis XP_852846 1254 149341 R337 W A W E R K E R L S A Q Q A R
Cat Felis silvestris
Mouse Mus musculus Q3UZY0 1216 144015 S311 W A W E W R Q S L S A H Q A L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517622 1137 134753 N358 R M R Q Q Q E N H L A E R M A
Chicken Gallus gallus XP_425281 812 97208 R87 R A V L H F E R Q L L V S F W
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780221 945 112945 K220 Y V I Q R R A K A I L K Q R A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 90.4 73 N.A. 63.2 N.A. N.A. 40.5 21 N.A. N.A. N.A. N.A. N.A. N.A. 21.3
Protein Similarity: 100 99 93.4 81.8 N.A. 73.8 N.A. N.A. 56.9 34.1 N.A. N.A. N.A. N.A. N.A. N.A. 35.9
P-Site Identity: 100 100 80 53.3 N.A. 60 N.A. N.A. 13.3 13.3 N.A. N.A. N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 100 66.6 N.A. 66.6 N.A. N.A. 46.6 20 N.A. N.A. N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 75 0 0 0 0 13 0 13 0 75 0 0 63 25 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 63 0 0 63 0 0 0 0 13 0 0 0 % E
% Phe: 0 0 0 0 0 13 0 0 0 0 0 0 0 13 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 13 0 0 0 13 0 0 38 38 0 0 % H
% Ile: 0 0 13 0 0 0 0 0 0 13 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 13 0 13 0 0 0 13 0 0 0 % K
% Leu: 0 0 0 13 0 0 0 0 63 25 25 0 0 0 13 % L
% Met: 0 13 0 0 0 0 0 0 0 0 0 0 0 13 0 % M
% Asn: 0 0 0 0 0 0 0 13 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 38 0 0 25 25 13 25 0 13 0 0 13 38 0 38 % Q
% Arg: 25 0 13 0 50 63 0 25 0 0 0 0 13 13 13 % R
% Ser: 0 0 0 0 0 0 0 50 0 25 0 0 13 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 13 13 0 0 0 0 0 0 0 0 13 0 0 0 % V
% Trp: 25 0 63 0 13 0 0 0 0 0 0 0 0 0 13 % W
% Tyr: 13 0 0 0 0 0 0 0 0 38 0 13 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _