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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERI2 All Species: 2.73
Human Site: S302 Identified Species: 6.67
UniProt: A8K979 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A8K979 NP_001136197.1 691 77401 S302 M K S I C A N S P I K A Q Q D
Chimpanzee Pan troglodytes XP_001149333 339 37621
Rhesus Macaque Macaca mulatta XP_001084714 279 31786
Dog Lupus familis XP_851106 279 32080
Cat Felis silvestris
Mouse Mus musculus Q5BKS4 688 76506 S302 M N S V C V N S S C I K G Q L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508438 683 74917 P302 F G K N N V S P N G R V R R G
Chicken Gallus gallus XP_424602 660 72304 T279 T E R S H N G T V G I V V N S
Frog Xenopus laevis Q5HZL1 687 75822 L302 V M N L Q K D L E P S S L K I
Zebra Danio Brachydanio rerio Q502M8 555 61627 N174 S V P E A L K N W I D L R A T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790825 613 66581 L232 L K A I P S A L P Q P G S A Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 48.6 38.7 36.3 N.A. 74.2 N.A. N.A. 55.7 44.1 48.1 34.4 N.A. N.A. N.A. N.A. 34.5
Protein Similarity: 100 49 39.7 38.3 N.A. 83.7 N.A. N.A. 68.5 59.7 63.9 51.3 N.A. N.A. N.A. N.A. 49.4
P-Site Identity: 100 0 0 0 N.A. 40 N.A. N.A. 0 0 0 6.6 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 0 0 0 N.A. 46.6 N.A. N.A. 26.6 13.3 40 20 N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 10 10 10 0 0 0 0 10 0 20 0 % A
% Cys: 0 0 0 0 20 0 0 0 0 10 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 10 0 0 0 10 0 0 0 10 % D
% Glu: 0 10 0 10 0 0 0 0 10 0 0 0 0 0 0 % E
% Phe: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 0 0 0 10 0 0 20 0 10 10 0 10 % G
% His: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 20 0 0 0 0 0 20 20 0 0 0 10 % I
% Lys: 0 20 10 0 0 10 10 0 0 0 10 10 0 10 0 % K
% Leu: 10 0 0 10 0 10 0 20 0 0 0 10 10 0 10 % L
% Met: 20 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 10 10 10 10 20 10 10 0 0 0 0 10 0 % N
% Pro: 0 0 10 0 10 0 0 10 20 10 10 0 0 0 0 % P
% Gln: 0 0 0 0 10 0 0 0 0 10 0 0 10 20 10 % Q
% Arg: 0 0 10 0 0 0 0 0 0 0 10 0 20 10 0 % R
% Ser: 10 0 20 10 0 10 10 20 10 0 10 10 10 0 10 % S
% Thr: 10 0 0 0 0 0 0 10 0 0 0 0 0 0 10 % T
% Val: 10 10 0 10 0 20 0 0 10 0 0 20 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _