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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERI2 All Species: 3.94
Human Site: T346 Identified Species: 9.63
UniProt: A8K979 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A8K979 NP_001136197.1 691 77401 T346 V G Q L Q S P T L N S P I Y M
Chimpanzee Pan troglodytes XP_001149333 339 37621
Rhesus Macaque Macaca mulatta XP_001084714 279 31786
Dog Lupus familis XP_851106 279 32080
Cat Felis silvestris
Mouse Mus musculus Q5BKS4 688 76506 T344 V D Q L H S P T L N P P L T M
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508438 683 74917 A343 P L S F H I N A P S A P S G K
Chicken Gallus gallus XP_424602 660 72304 R320 T D L C E E T R S S S T V S Q
Frog Xenopus laevis Q5HZL1 687 75822 L345 I N G L S T T L G N G P K R C
Zebra Danio Brachydanio rerio Q502M8 555 61627 A215 E H S G L V D A R N T A L L A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790825 613 66581 S273 T T P T T S L S K A L S S S S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 48.6 38.7 36.3 N.A. 74.2 N.A. N.A. 55.7 44.1 48.1 34.4 N.A. N.A. N.A. N.A. 34.5
Protein Similarity: 100 49 39.7 38.3 N.A. 83.7 N.A. N.A. 68.5 59.7 63.9 51.3 N.A. N.A. N.A. N.A. 49.4
P-Site Identity: 100 0 0 0 N.A. 66.6 N.A. N.A. 6.6 6.6 20 6.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 0 0 0 N.A. 73.3 N.A. N.A. 20 26.6 33.3 20 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 20 0 10 10 10 0 0 10 % A
% Cys: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 10 % C
% Asp: 0 20 0 0 0 0 10 0 0 0 0 0 0 0 0 % D
% Glu: 10 0 0 0 10 10 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 10 10 0 0 0 0 10 0 10 0 0 10 0 % G
% His: 0 10 0 0 20 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 10 0 0 0 0 0 0 10 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 10 0 0 0 10 0 10 % K
% Leu: 0 10 10 30 10 0 10 10 20 0 10 0 20 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20 % M
% Asn: 0 10 0 0 0 0 10 0 0 40 0 0 0 0 0 % N
% Pro: 10 0 10 0 0 0 20 0 10 0 10 40 0 0 0 % P
% Gln: 0 0 20 0 10 0 0 0 0 0 0 0 0 0 10 % Q
% Arg: 0 0 0 0 0 0 0 10 10 0 0 0 0 10 0 % R
% Ser: 0 0 20 0 10 30 0 10 10 20 20 10 20 20 10 % S
% Thr: 20 10 0 10 10 10 20 20 0 0 10 10 0 10 0 % T
% Val: 20 0 0 0 0 10 0 0 0 0 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _