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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERI2
All Species:
2.73
Human Site:
T578
Identified Species:
6.67
UniProt:
A8K979
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A8K979
NP_001136197.1
691
77401
T578
R
R
L
P
S
I
L
T
S
T
V
N
L
Q
E
Chimpanzee
Pan troglodytes
XP_001149333
339
37621
S227
R
L
P
S
I
L
T
S
T
V
N
L
Q
E
P
Rhesus Macaque
Macaca mulatta
XP_001084714
279
31786
R167
C
L
E
Y
E
C
K
R
K
Q
L
L
K
P
V
Dog
Lupus familis
XP_851106
279
32080
R167
C
L
E
Y
E
C
K
R
K
Q
L
L
K
P
V
Cat
Felis silvestris
Mouse
Mus musculus
Q5BKS4
688
76506
S576
V
S
P
S
V
L
T
S
T
V
N
L
Q
E
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508438
683
74917
G571
T
D
G
P
R
T
P
G
G
R
S
A
R
K
V
Chicken
Gallus gallus
XP_424602
660
72304
A548
N
L
S
K
A
S
R
A
V
L
S
S
T
V
N
Frog
Xenopus laevis
Q5HZL1
687
75822
L574
H
N
V
P
P
T
V
L
N
A
T
V
N
N
T
Zebra Danio
Brachydanio rerio
Q502M8
555
61627
K443
C
V
S
S
S
V
F
K
T
P
P
P
L
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790825
613
66581
I501
P
G
V
C
M
A
K
I
T
P
P
M
C
K
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
48.6
38.7
36.3
N.A.
74.2
N.A.
N.A.
55.7
44.1
48.1
34.4
N.A.
N.A.
N.A.
N.A.
34.5
Protein Similarity:
100
49
39.7
38.3
N.A.
83.7
N.A.
N.A.
68.5
59.7
63.9
51.3
N.A.
N.A.
N.A.
N.A.
49.4
P-Site Identity:
100
6.6
0
0
N.A.
0
N.A.
N.A.
6.6
0
6.6
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
33.3
6.6
6.6
N.A.
26.6
N.A.
N.A.
13.3
13.3
26.6
26.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
10
0
10
0
10
0
10
0
0
0
% A
% Cys:
30
0
0
10
0
20
0
0
0
0
0
0
10
0
10
% C
% Asp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
20
0
20
0
0
0
0
0
0
0
0
20
10
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
10
0
0
0
0
10
10
0
0
0
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
10
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
30
10
20
0
0
0
20
20
0
% K
% Leu:
0
40
10
0
0
20
10
10
0
10
20
40
20
10
0
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
10
10
0
0
0
0
0
0
10
0
20
10
10
10
10
% N
% Pro:
10
0
20
30
10
0
10
0
0
20
20
10
0
20
20
% P
% Gln:
0
0
0
0
0
0
0
0
0
20
0
0
20
10
0
% Q
% Arg:
20
10
0
0
10
0
10
20
0
10
0
0
10
0
10
% R
% Ser:
0
10
20
30
20
10
0
20
10
0
20
10
0
0
0
% S
% Thr:
10
0
0
0
0
20
20
10
40
10
10
0
10
0
10
% T
% Val:
10
10
20
0
10
10
10
0
10
20
10
10
0
10
30
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
20
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _