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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERI2
All Species:
1.52
Human Site:
Y620
Identified Species:
3.7
UniProt:
A8K979
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A8K979
NP_001136197.1
691
77401
Y620
P
N
H
G
K
V
F
Y
C
C
P
I
G
K
Y
Chimpanzee
Pan troglodytes
XP_001149333
339
37621
C269
N
H
G
K
V
F
Y
C
C
P
I
G
K
Y
Q
Rhesus Macaque
Macaca mulatta
XP_001084714
279
31786
S209
Q
E
V
G
I
E
F
S
G
R
E
H
S
G
L
Dog
Lupus familis
XP_851106
279
32080
L209
Q
E
V
G
I
E
F
L
G
Q
E
H
S
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q5BKS4
688
76506
C618
N
H
G
K
A
F
Y
C
C
P
V
G
K
Y
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508438
683
74917
R613
N
C
G
R
R
A
K
R
L
V
V
S
N
N
G
Chicken
Gallus gallus
XP_424602
660
72304
N590
Y
V
S
N
A
G
P
N
H
G
K
A
F
F
C
Frog
Xenopus laevis
Q5HZL1
687
75822
A616
A
G
P
N
Q
G
K
A
F
Y
T
C
S
V
K
Zebra Danio
Brachydanio rerio
Q502M8
555
61627
S485
K
Q
K
V
K
V
T
S
P
L
C
V
C
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790825
613
66581
K543
R
R
S
G
G
G
L
K
D
T
T
N
A
K
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
48.6
38.7
36.3
N.A.
74.2
N.A.
N.A.
55.7
44.1
48.1
34.4
N.A.
N.A.
N.A.
N.A.
34.5
Protein Similarity:
100
49
39.7
38.3
N.A.
83.7
N.A.
N.A.
68.5
59.7
63.9
51.3
N.A.
N.A.
N.A.
N.A.
49.4
P-Site Identity:
100
6.6
13.3
13.3
N.A.
6.6
N.A.
N.A.
0
0
0
13.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
20
13.3
13.3
N.A.
20
N.A.
N.A.
6.6
0
6.6
20
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
20
10
0
10
0
0
0
10
10
0
0
% A
% Cys:
0
10
0
0
0
0
0
20
30
10
10
10
10
0
10
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
20
0
0
0
20
0
0
0
0
20
0
0
0
0
% E
% Phe:
0
0
0
0
0
20
30
0
10
0
0
0
10
10
0
% F
% Gly:
0
10
30
40
10
30
0
0
20
10
0
20
10
30
10
% G
% His:
0
20
10
0
0
0
0
0
10
0
0
20
0
0
0
% H
% Ile:
0
0
0
0
20
0
0
0
0
0
10
10
0
0
0
% I
% Lys:
10
0
10
20
20
0
20
10
0
0
10
0
20
20
10
% K
% Leu:
0
0
0
0
0
0
10
10
10
10
0
0
0
0
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
30
10
0
20
0
0
0
10
0
0
0
10
10
10
0
% N
% Pro:
10
0
10
0
0
0
10
0
10
20
10
0
0
0
0
% P
% Gln:
20
10
0
0
10
0
0
0
0
10
0
0
0
0
20
% Q
% Arg:
10
10
0
10
10
0
0
10
0
10
0
0
0
0
10
% R
% Ser:
0
0
20
0
0
0
0
20
0
0
0
10
30
0
0
% S
% Thr:
0
0
0
0
0
0
10
0
0
10
20
0
0
0
0
% T
% Val:
0
10
20
10
10
20
0
0
0
10
20
10
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
20
10
0
10
0
0
0
20
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _