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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 22.12
Human Site: S591 Identified Species: 37.44
UniProt: A8MPP1 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A8MPP1 NP_085911 907 101811 S591 V I L S R Q G S L S E S T L K
Chimpanzee Pan troglodytes XP_520821 925 103112 S608 V I L S R Q G S L S Q S T L K
Rhesus Macaque Macaca mulatta XP_001114510 906 101461 S589 V I L S R Q G S L S Q S T L K
Dog Lupus familis XP_543872 907 102087 S590 V I L S R Q G S L S Q S S L K
Cat Felis silvestris
Mouse Mus musculus Q6AXC6 880 98710 G560 R V I V N R Q G S V G Q S S L
Rat Rattus norvegicus XP_001070646 845 94905 S526 V I V N R Q G S V G Q S S L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517598 930 104705 S620 I I L N H Q S S L S L S S L K
Chicken Gallus gallus XP_416375 940 105739 I620 A N E D G R V I L N R Q G T I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001007320 890 100643 I567 N K D G R I V I Q R Q A C V A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_569898 861 96577 G563 I L V D P V G G T L K Y I L L
Honey Bee Apis mellifera XP_001121183 769 88327 V515 V T F S C D H V I P K E N I I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792082 780 88384 S519 P E R I L E F S C G H V I P P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P22516 861 98787 V579 I L N Q A K C V V L A G G T M
Red Bread Mold Neurospora crassa A7UXD4 1073 119198 H694 Y M L L S P T H A F S S I A E
Conservation
Percent
Protein Identity: 100 93.9 96.2 83.1 N.A. 76.9 71.7 N.A. 73.5 68.1 N.A. 59.9 N.A. 39.2 38.1 N.A. 46.6
Protein Similarity: 100 95.6 97.4 90.1 N.A. 84.9 80.3 N.A. 83.5 80.3 N.A. 76.1 N.A. 56.1 56.1 N.A. 62.6
P-Site Identity: 100 93.3 93.3 86.6 N.A. 0 60 N.A. 60 6.6 N.A. 6.6 N.A. 13.3 13.3 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 26.6 93.3 N.A. 80 20 N.A. 26.6 N.A. 40 33.3 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 32.4 28.5
Protein Similarity: N.A. N.A. N.A. N.A. 51.1 44.7
P-Site Identity: N.A. N.A. N.A. N.A. 0 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 8 0 0 0 8 0 8 8 0 8 8 % A
% Cys: 0 0 0 0 8 0 8 0 8 0 0 0 8 0 0 % C
% Asp: 0 0 8 15 0 8 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 8 8 0 0 8 0 0 0 0 8 8 0 0 8 % E
% Phe: 0 0 8 0 0 0 8 0 0 8 0 0 0 0 0 % F
% Gly: 0 0 0 8 8 0 43 15 0 15 8 8 15 0 0 % G
% His: 0 0 0 0 8 0 8 8 0 0 8 0 0 0 0 % H
% Ile: 22 43 8 8 0 8 0 15 8 0 0 0 22 8 15 % I
% Lys: 0 8 0 0 0 8 0 0 0 0 15 0 0 0 43 % K
% Leu: 0 15 43 8 8 0 0 0 43 15 8 0 0 50 15 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 8 8 8 15 8 0 0 0 0 8 0 0 8 0 0 % N
% Pro: 8 0 0 0 8 8 0 0 0 8 0 0 0 8 8 % P
% Gln: 0 0 0 8 0 43 8 0 8 0 36 15 0 0 0 % Q
% Arg: 8 0 8 0 43 15 0 0 0 8 8 0 0 0 0 % R
% Ser: 0 0 0 36 8 0 8 50 8 36 8 50 29 8 0 % S
% Thr: 0 8 0 0 0 0 8 0 8 0 0 0 22 15 0 % T
% Val: 43 8 15 8 0 8 15 15 15 8 0 8 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _