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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 18.18
Human Site: T104 Identified Species: 30.77
UniProt: A8MPP1 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A8MPP1 NP_085911 907 101811 T104 S C E G A A G T P R P A G E P
Chimpanzee Pan troglodytes XP_520821 925 103112 T123 S C E G A A G T P R P A G E P
Rhesus Macaque Macaca mulatta XP_001114510 906 101461 T104 S C K G A A A T P R P A G E P
Dog Lupus familis XP_543872 907 102087 T104 S C K R T P D T L S P A G E P
Cat Felis silvestris
Mouse Mus musculus Q6AXC6 880 98710 T101 S S S C Q E P T D T P R P A G
Rat Rattus norvegicus XP_001070646 845 94905 T103 S C Q E P S D T L R P A G D P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517598 930 104705 I135 S A G E P D W I T Q F V Q K K
Chicken Gallus gallus XP_416375 940 105739 S136 G G P A C P N S R D A S G E P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001007320 890 100643 V100 P D W V S E F V Q K K A E R D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_569898 861 96577 Q112 S Q G K S R A Q R A E L L R L
Honey Bee Apis mellifera XP_001121183 769 88327 I99 Q N E T D N S I D E N N K N E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792082 780 88384 I101 E P E E I T K I F Y C S R T H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P22516 861 98787 T129 T S C K Q L K T M C D L D K E
Red Bread Mold Neurospora crassa A7UXD4 1073 119198 L213 I K R K R E E L A Q K Y E E M
Conservation
Percent
Protein Identity: 100 93.9 96.2 83.1 N.A. 76.9 71.7 N.A. 73.5 68.1 N.A. 59.9 N.A. 39.2 38.1 N.A. 46.6
Protein Similarity: 100 95.6 97.4 90.1 N.A. 84.9 80.3 N.A. 83.5 80.3 N.A. 76.1 N.A. 56.1 56.1 N.A. 62.6
P-Site Identity: 100 100 86.6 53.3 N.A. 20 53.3 N.A. 6.6 20 N.A. 6.6 N.A. 6.6 6.6 N.A. 6.6
P-Site Similarity: 100 100 93.3 60 N.A. 20 73.3 N.A. 20 33.3 N.A. 20 N.A. 13.3 6.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 32.4 28.5
Protein Similarity: N.A. N.A. N.A. N.A. 51.1 44.7
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 20 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 8 22 22 15 0 8 8 8 43 0 8 0 % A
% Cys: 0 36 8 8 8 0 0 0 0 8 8 0 0 0 0 % C
% Asp: 0 8 0 0 8 8 15 0 15 8 8 0 8 8 8 % D
% Glu: 8 0 29 22 0 22 8 0 0 8 8 0 15 43 15 % E
% Phe: 0 0 0 0 0 0 8 0 8 0 8 0 0 0 0 % F
% Gly: 8 8 15 22 0 0 15 0 0 0 0 0 43 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 8 0 0 0 8 0 0 22 0 0 0 0 0 0 0 % I
% Lys: 0 8 15 22 0 0 15 0 0 8 15 0 8 15 8 % K
% Leu: 0 0 0 0 0 8 0 8 15 0 0 15 8 0 8 % L
% Met: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 8 % M
% Asn: 0 8 0 0 0 8 8 0 0 0 8 8 0 8 0 % N
% Pro: 8 8 8 0 15 15 8 0 22 0 43 0 8 0 43 % P
% Gln: 8 8 8 0 15 0 0 8 8 15 0 0 8 0 0 % Q
% Arg: 0 0 8 8 8 8 0 0 15 29 0 8 8 15 0 % R
% Ser: 58 15 8 0 15 8 8 8 0 8 0 15 0 0 0 % S
% Thr: 8 0 0 8 8 8 0 50 8 8 0 0 0 8 0 % T
% Val: 0 0 0 8 0 0 0 8 0 0 0 8 0 0 0 % V
% Trp: 0 0 8 0 0 0 8 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 8 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _