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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 30.91
Human Site: Y116 Identified Species: 68
UniProt: A8MSY0 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A8MSY0 NP_054907 194 22430 Y116 F T C E E S V Y D T V V E D L
Chimpanzee Pan troglodytes XP_001152323 228 26252 Y150 F T C E E S V Y D T V V E D L
Rhesus Macaque Macaca mulatta XP_001082455 194 22283 Y116 F T C E E S V Y D T V V E D L
Dog Lupus familis XP_536707 194 22568 Y116 L T C E E R V Y D Q V V E D L
Cat Felis silvestris
Mouse Mus musculus Q9CY97 194 22499 Y116 L T C E E R V Y D Q V V E D L
Rat Rattus norvegicus Q4KLK9 194 22526 Y116 L T C E E R V Y D Q V V E D L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZJQ7 194 22556 Y116 L T C E E R V Y D Q V V E D L
Frog Xenopus laevis Q6NRQ7 194 22662 Y116 I T C E E R V Y D Q V V E E L
Zebra Danio Brachydanio rerio Q6PC19 194 22774 Y116 I T C E E R V Y D Q V L E D L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53538 206 23451 F119 F T C E E R C F D A V C E D L
Red Bread Mold Neurospora crassa Q7SFY0 266 29401 W166 I T C E E R C W D A V I E D L
Conservation
Percent
Protein Identity: 100 82.4 92.2 71.6 N.A. 71.6 71.1 N.A. N.A. 71.6 66.4 67 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 84.2 96.9 85.5 N.A. 86 85.5 N.A. N.A. 85.5 85.5 83.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 80 N.A. 80 80 N.A. N.A. 80 73.3 73.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 80 N.A. 80 80 N.A. N.A. 80 80 80 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 39.3 30.8
Protein Similarity: N.A. N.A. N.A. N.A. 60.6 45.8
P-Site Identity: N.A. N.A. N.A. N.A. 66.6 60
P-Site Similarity: N.A. N.A. N.A. N.A. 73.3 73.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 19 0 0 0 0 0 % A
% Cys: 0 0 100 0 0 0 19 0 0 0 0 10 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 100 0 0 0 0 91 0 % D
% Glu: 0 0 0 100 100 0 0 0 0 0 0 0 100 10 0 % E
% Phe: 37 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 28 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 37 0 0 0 0 0 0 0 0 0 0 10 0 0 100 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 55 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 73 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 28 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 100 0 0 0 0 0 0 0 28 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 82 0 0 0 100 73 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 82 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _