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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 8.79
Human Site: S477 Identified Species: 17.58
UniProt: A8MT19 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A8MT19 NP_149094 583 65945 S477 E V M K L L K S F G E D E I E
Chimpanzee Pan troglodytes XP_001152684 686 76936 S580 E V M K L L K S F G E D E I E
Rhesus Macaque Macaca mulatta XP_001107427 591 66623 F486 K L G P L S V F S A N K R W T
Dog Lupus familis XP_539197 623 67119 V498 A K N C W R L V G P V H M T R
Cat Felis silvestris
Mouse Mus musculus Q8BWR8 686 76939 S580 E V M K L L K S F G G E E V E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509093 779 87744 L673 V S E V M Q T L K S F E E Q D
Chicken Gallus gallus XP_414133 679 76430 L574 V N E V L E K L K S V G E Q P
Frog Xenopus laevis Q6DJJ6 683 77116 L577 T S Q V M D M L Q A T G K Q S
Zebra Danio Brachydanio rerio Q6TNR1 683 77039 L577 G V S D V M K L L K D V D E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_511168 718 80809 L598 A H V E I N S L A D L G G I K
Honey Bee Apis mellifera XP_001120267 660 74505 G555 D L G G M K E G D F I V G I G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785878 687 77731 A558 E V V K S I L A S P H R I K L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77.9 71.9 29.7 N.A. 67.1 N.A. N.A. 54.5 56.2 49.6 45.2 N.A. 26.4 33.7 N.A. 31
Protein Similarity: 100 79.7 74.6 45.2 N.A. 73.7 N.A. N.A. 62.9 68 62.8 62.2 N.A. 41.9 50.9 N.A. 48.3
P-Site Identity: 100 100 6.6 0 N.A. 80 N.A. N.A. 6.6 20 0 20 N.A. 6.6 6.6 N.A. 20
P-Site Similarity: 100 100 20 0 N.A. 93.3 N.A. N.A. 26.6 20 13.3 46.6 N.A. 33.3 33.3 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 0 0 0 0 0 9 9 17 0 0 0 0 0 % A
% Cys: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 9 0 9 0 0 9 9 9 17 9 0 9 % D
% Glu: 34 0 17 9 0 9 9 0 0 0 17 17 42 9 34 % E
% Phe: 0 0 0 0 0 0 0 9 25 9 9 0 0 0 0 % F
% Gly: 9 0 17 9 0 0 0 9 9 25 9 25 17 0 9 % G
% His: 0 9 0 0 0 0 0 0 0 0 9 9 0 0 0 % H
% Ile: 0 0 0 0 9 9 0 0 0 0 9 0 9 34 0 % I
% Lys: 9 9 0 34 0 9 42 0 17 9 0 9 9 9 9 % K
% Leu: 0 17 0 0 42 25 17 42 9 0 9 0 0 0 9 % L
% Met: 0 0 25 0 25 9 9 0 0 0 0 0 9 0 0 % M
% Asn: 0 9 9 0 0 9 0 0 0 0 9 0 0 0 0 % N
% Pro: 0 0 0 9 0 0 0 0 0 17 0 0 0 0 9 % P
% Gln: 0 0 9 0 0 9 0 0 9 0 0 0 0 25 0 % Q
% Arg: 0 0 0 0 0 9 0 0 0 0 0 9 9 0 9 % R
% Ser: 0 17 9 0 9 9 9 25 17 17 0 0 0 0 9 % S
% Thr: 9 0 0 0 0 0 9 0 0 0 9 0 0 9 9 % T
% Val: 17 42 17 25 9 0 9 9 0 0 17 17 0 9 0 % V
% Trp: 0 0 0 0 9 0 0 0 0 0 0 0 0 9 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _