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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 12.12
Human Site: S574 Identified Species: 24.24
UniProt: A8MT19 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A8MT19 NP_149094 583 65945 S574 K K L P S P F S L L N S D S S
Chimpanzee Pan troglodytes XP_001152684 686 76936 S677 K K L P S P F S L L N P D S S
Rhesus Macaque Macaca mulatta XP_001107427 591 66623 S583 D S T S S M V S A D T S L G S
Dog Lupus familis XP_539197 623 67119 W595 R F L P S V A W C A H A L T A
Cat Felis silvestris
Mouse Mus musculus Q8BWR8 686 76939 S677 K K L P T P F S L L N S D S S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509093 779 87744 G770 K K L P S P F G L L N T D S S
Chicken Gallus gallus XP_414133 679 76430 L671 K K L S P F T L L G T E S S L
Frog Xenopus laevis Q6DJJ6 683 77116 N674 N L F S F P D N S L C S E S V
Zebra Danio Brachydanio rerio Q6TNR1 683 77039 S674 N R P S A N Y S N S H H E S G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_511168 718 80809 R695 L K T S S S S R P A G S V S S
Honey Bee Apis mellifera XP_001120267 660 74505 L652 T Q R D S R D L T F D N V I L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785878 687 77731 K655 I T S T D G G K G S T G K K K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77.9 71.9 29.7 N.A. 67.1 N.A. N.A. 54.5 56.2 49.6 45.2 N.A. 26.4 33.7 N.A. 31
Protein Similarity: 100 79.7 74.6 45.2 N.A. 73.7 N.A. N.A. 62.9 68 62.8 62.2 N.A. 41.9 50.9 N.A. 48.3
P-Site Identity: 100 93.3 26.6 20 N.A. 93.3 N.A. N.A. 86.6 33.3 26.6 13.3 N.A. 33.3 6.6 N.A. 0
P-Site Similarity: 100 93.3 26.6 53.3 N.A. 100 N.A. N.A. 93.3 33.3 40 46.6 N.A. 33.3 26.6 N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 9 0 9 0 9 17 0 9 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 9 0 9 0 0 0 0 % C
% Asp: 9 0 0 9 9 0 17 0 0 9 9 0 34 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 9 17 0 0 % E
% Phe: 0 9 9 0 9 9 34 0 0 9 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 9 9 9 9 9 9 9 0 9 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 17 9 0 0 0 % H
% Ile: 9 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % I
% Lys: 42 50 0 0 0 0 0 9 0 0 0 0 9 9 9 % K
% Leu: 9 9 50 0 0 0 0 17 42 42 0 0 17 0 17 % L
% Met: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % M
% Asn: 17 0 0 0 0 9 0 9 9 0 34 9 0 0 0 % N
% Pro: 0 0 9 42 9 42 0 0 9 0 0 9 0 0 0 % P
% Gln: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 9 9 9 0 0 9 0 9 0 0 0 0 0 0 0 % R
% Ser: 0 9 9 42 59 9 9 42 9 17 0 42 9 67 50 % S
% Thr: 9 9 17 9 9 0 9 0 9 0 25 9 0 9 0 % T
% Val: 0 0 0 0 0 9 9 0 0 0 0 0 17 0 9 % V
% Trp: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _