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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NOTO
All Species:
9.09
Human Site:
S228
Identified Species:
25
UniProt:
A8MTQ0
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A8MTQ0
NP_001127934.1
251
27003
S228
V
T
S
A
E
A
A
S
L
D
E
P
S
S
S
Chimpanzee
Pan troglodytes
XP_525785
278
29856
S255
V
T
S
A
E
A
A
S
L
D
E
P
S
S
S
Rhesus Macaque
Macaca mulatta
XP_001095400
251
27124
S228
V
T
S
A
E
A
A
S
L
D
E
P
S
S
S
Dog
Lupus familis
XP_855173
287
30754
P264
A
V
S
A
V
A
A
P
Q
D
E
P
S
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q5TIS6
240
26304
V217
L
K
L
P
S
S
S
V
M
E
E
P
S
S
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515517
289
30158
P265
A
K
L
A
L
L
V
P
R
P
R
A
P
P
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Q91770
233
26710
V207
A
K
L
S
Q
F
G
V
I
L
A
D
S
S
D
Zebra Danio
Brachydanio rerio
Q804S6
231
26490
K205
P
E
C
T
Q
K
K
K
G
N
H
H
I
N
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Q26657
327
37128
H284
P
R
L
H
P
H
P
H
F
G
P
I
L
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.5
91.6
43.9
N.A.
55.3
N.A.
N.A.
32.1
N.A.
30.2
25.5
N.A.
N.A.
N.A.
N.A.
21.7
Protein Similarity:
100
89.5
93.6
50.1
N.A.
64.1
N.A.
N.A.
42.2
N.A.
47
37.8
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Identity:
100
100
100
66.6
N.A.
33.3
N.A.
N.A.
13.3
N.A.
13.3
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
66.6
N.A.
66.6
N.A.
N.A.
13.3
N.A.
33.3
20
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
0
0
56
0
45
45
0
0
0
12
12
0
0
0
% A
% Cys:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
45
0
12
0
0
12
% D
% Glu:
0
12
0
0
34
0
0
0
0
12
56
0
0
0
0
% E
% Phe:
0
0
0
0
0
12
0
0
12
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
12
0
12
12
0
0
0
12
12
% G
% His:
0
0
0
12
0
12
0
12
0
0
12
12
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
12
0
0
12
12
0
0
% I
% Lys:
0
34
0
0
0
12
12
12
0
0
0
0
0
0
0
% K
% Leu:
12
0
45
0
12
12
0
0
34
12
0
0
12
0
0
% L
% Met:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
12
0
0
0
12
0
% N
% Pro:
23
0
0
12
12
0
12
23
0
12
12
56
12
12
0
% P
% Gln:
0
0
0
0
23
0
0
0
12
0
0
0
0
0
0
% Q
% Arg:
0
12
0
0
0
0
0
0
12
0
12
0
0
0
12
% R
% Ser:
0
0
45
12
12
12
12
34
0
0
0
0
67
67
67
% S
% Thr:
0
34
0
12
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
34
12
0
0
12
0
12
23
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _