KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NOTO
All Species:
12.12
Human Site:
S247
Identified Species:
33.33
UniProt:
A8MTQ0
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A8MTQ0
NP_001127934.1
251
27003
S247
I
Q
S
D
D
A
E
S
G
V
D
G
_
_
_
Chimpanzee
Pan troglodytes
XP_525785
278
29856
S274
I
Q
S
D
D
A
E
S
G
V
D
G
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001095400
251
27124
S247
I
Q
S
D
D
A
G
S
G
V
D
G
_
_
_
Dog
Lupus familis
XP_855173
287
30754
S283
I
Q
R
E
D
T
E
S
G
V
D
S
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q5TIS6
240
26304
L236
I
Q
S
E
D
A
E
L
G
I
G
S
_
_
_
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515517
289
30158
A284
D
P
S
D
G
D
D
A
L
D
V
D
N
_
_
Chicken
Gallus gallus
Frog
Xenopus laevis
Q91770
233
26710
E226
S
R
E
T
E
E
E
E
D
D
V
D
V
E
L
Zebra Danio
Brachydanio rerio
Q804S6
231
26490
D224
T
K
Q
T
G
S
E
D
I
D
V
M
S
D
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Q26657
327
37128
L303
S
N
L
V
S
S
H
L
C
R
L
A
C
I
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.5
91.6
43.9
N.A.
55.3
N.A.
N.A.
32.1
N.A.
30.2
25.5
N.A.
N.A.
N.A.
N.A.
21.7
Protein Similarity:
100
89.5
93.6
50.1
N.A.
64.1
N.A.
N.A.
42.2
N.A.
47
37.8
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Identity:
100
100
91.6
66.6
N.A.
58.3
N.A.
N.A.
15.3
N.A.
6.6
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
91.6
75
N.A.
75
N.A.
N.A.
30.7
N.A.
20
20
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
45
0
12
0
0
0
12
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
12
0
0
0
12
0
0
% C
% Asp:
12
0
0
45
56
12
12
12
12
34
45
23
0
12
12
% D
% Glu:
0
0
12
23
12
12
67
12
0
0
0
0
0
12
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
23
0
12
0
56
0
12
34
0
0
0
% G
% His:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% H
% Ile:
56
0
0
0
0
0
0
0
12
12
0
0
0
12
0
% I
% Lys:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
12
0
0
0
0
23
12
0
12
0
0
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% M
% Asn:
0
12
0
0
0
0
0
0
0
0
0
0
12
0
0
% N
% Pro:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
56
12
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
12
12
0
0
0
0
0
0
12
0
0
0
0
0
% R
% Ser:
23
0
56
0
12
23
0
45
0
0
0
23
12
0
0
% S
% Thr:
12
0
0
23
0
12
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
12
0
0
0
0
0
45
34
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
56
67
67
% _