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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NOTO All Species: 11.52
Human Site: S47 Identified Species: 31.67
UniProt: A8MTQ0 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A8MTQ0 NP_001127934.1 251 27003 S47 R A P G R F E S P F S V E A I
Chimpanzee Pan troglodytes XP_525785 278 29856 S47 R A P G R F E S P F S V E A I
Rhesus Macaque Macaca mulatta XP_001095400 251 27124 S47 R A P R R F E S P F S V E A I
Dog Lupus familis XP_855173 287 30754 S55 G V D S A R G S A G R G G G T
Cat Felis silvestris
Mouse Mus musculus Q5TIS6 240 26304 A47 F S V E A I L A R P K T R E L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515517 289 30158 T69 P A S A R Q L T S F H I D S I
Chicken Gallus gallus
Frog Xenopus laevis Q91770 233 26710 A47 L S R T D R P A S K V S M E M
Zebra Danio Brachydanio rerio Q804S6 231 26490 Q47 D S F L N G Y Q S P A G R A L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus Q26657 327 37128 V69 L A G M T G S V G K C N D M M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.5 91.6 43.9 N.A. 55.3 N.A. N.A. 32.1 N.A. 30.2 25.5 N.A. N.A. N.A. N.A. 21.7
Protein Similarity: 100 89.5 93.6 50.1 N.A. 64.1 N.A. N.A. 42.2 N.A. 47 37.8 N.A. N.A. N.A. N.A. 33.3
P-Site Identity: 100 100 93.3 6.6 N.A. 0 N.A. N.A. 26.6 N.A. 0 6.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 93.3 6.6 N.A. 20 N.A. N.A. 53.3 N.A. 20 26.6 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 56 0 12 23 0 0 23 12 0 12 0 0 45 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % C
% Asp: 12 0 12 0 12 0 0 0 0 0 0 0 23 0 0 % D
% Glu: 0 0 0 12 0 0 34 0 0 0 0 0 34 23 0 % E
% Phe: 12 0 12 0 0 34 0 0 0 45 0 0 0 0 0 % F
% Gly: 12 0 12 23 0 23 12 0 12 12 0 23 12 12 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % H
% Ile: 0 0 0 0 0 12 0 0 0 0 0 12 0 0 45 % I
% Lys: 0 0 0 0 0 0 0 0 0 23 12 0 0 0 0 % K
% Leu: 23 0 0 12 0 0 23 0 0 0 0 0 0 0 23 % L
% Met: 0 0 0 12 0 0 0 0 0 0 0 0 12 12 23 % M
% Asn: 0 0 0 0 12 0 0 0 0 0 0 12 0 0 0 % N
% Pro: 12 0 34 0 0 0 12 0 34 23 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 12 0 12 0 0 0 0 0 0 0 % Q
% Arg: 34 0 12 12 45 23 0 0 12 0 12 0 23 0 0 % R
% Ser: 0 34 12 12 0 0 12 45 34 0 34 12 0 12 0 % S
% Thr: 0 0 0 12 12 0 0 12 0 0 0 12 0 0 12 % T
% Val: 0 12 12 0 0 0 0 12 0 0 12 34 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _