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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NOTO
All Species:
9.7
Human Site:
S69
Identified Species:
26.67
UniProt:
A8MTQ0
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A8MTQ0
NP_001127934.1
251
27003
S69
A
P
A
A
S
Q
P
S
G
S
A
C
V
H
P
Chimpanzee
Pan troglodytes
XP_525785
278
29856
S69
A
P
A
A
S
Q
P
S
G
S
A
C
V
H
P
Rhesus Macaque
Macaca mulatta
XP_001095400
251
27124
S69
T
P
A
A
S
Q
P
S
G
S
A
C
A
H
P
Dog
Lupus familis
XP_855173
287
30754
R79
Q
H
R
A
A
R
R
R
Q
A
R
G
G
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q5TIS6
240
26304
L70
T
C
T
S
L
N
L
L
G
A
V
S
Q
Y
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515517
289
30158
P93
S
E
P
P
G
P
P
P
G
P
G
P
W
L
P
Chicken
Gallus gallus
Frog
Xenopus laevis
Q91770
233
26710
Y68
S
P
P
F
H
Y
S
Y
G
M
V
P
Y
P
P
Zebra Danio
Brachydanio rerio
Q804S6
231
26490
P70
S
E
T
V
N
H
A
P
L
S
M
H
P
H
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Q26657
327
37128
K94
R
M
T
D
A
R
V
K
D
N
E
Q
V
F
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.5
91.6
43.9
N.A.
55.3
N.A.
N.A.
32.1
N.A.
30.2
25.5
N.A.
N.A.
N.A.
N.A.
21.7
Protein Similarity:
100
89.5
93.6
50.1
N.A.
64.1
N.A.
N.A.
42.2
N.A.
47
37.8
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Identity:
100
100
86.6
6.6
N.A.
6.6
N.A.
N.A.
20
N.A.
20
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
86.6
26.6
N.A.
26.6
N.A.
N.A.
26.6
N.A.
26.6
26.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
23
0
34
45
23
0
12
0
0
23
34
0
12
0
0
% A
% Cys:
0
12
0
0
0
0
0
0
0
0
0
34
0
0
0
% C
% Asp:
0
0
0
12
0
0
0
0
12
0
0
0
0
0
0
% D
% Glu:
0
23
0
0
0
0
0
0
0
0
12
0
0
0
0
% E
% Phe:
0
0
0
12
0
0
0
0
0
0
0
0
0
12
0
% F
% Gly:
0
0
0
0
12
0
0
0
67
0
12
12
12
12
12
% G
% His:
0
12
0
0
12
12
0
0
0
0
0
12
0
45
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
12
0
12
12
12
0
0
0
0
12
0
% L
% Met:
0
12
0
0
0
0
0
0
0
12
12
0
0
0
0
% M
% Asn:
0
0
0
0
12
12
0
0
0
12
0
0
0
0
0
% N
% Pro:
0
45
23
12
0
12
45
23
0
12
0
23
12
12
56
% P
% Gln:
12
0
0
0
0
34
0
0
12
0
0
12
12
0
12
% Q
% Arg:
12
0
12
0
0
23
12
12
0
0
12
0
0
0
0
% R
% Ser:
34
0
0
12
34
0
12
34
0
45
0
12
0
0
12
% S
% Thr:
23
0
34
0
0
0
0
0
0
0
0
0
0
0
12
% T
% Val:
0
0
0
12
0
0
12
0
0
0
23
0
34
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% W
% Tyr:
0
0
0
0
0
12
0
12
0
0
0
0
12
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _