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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SMTNL1 All Species: 17.27
Human Site: S241 Identified Species: 42.22
UniProt: A8MU46 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A8MU46 NP_001099035 457 48953 S241 S P E E W P E S P T G E G H N
Chimpanzee Pan troglodytes XP_508434 474 50826 S258 S P E E W P E S P T G E G H N
Rhesus Macaque Macaca mulatta XP_001092494 467 50032 S251 S P E E W P E S P T G D G H N
Dog Lupus familis XP_849804 465 49062 S248 S P E E W L E S P T E E G S G
Cat Felis silvestris
Mouse Mus musculus Q99LM3 459 49507 P243 P S S P E E W P E S P T D E G
Rat Rattus norvegicus XP_230278 470 50583 S254 S P E D W P E S P T D E G T S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507534 1002 108621 E740 V S T I T K T E R L V H S N E
Chicken Gallus gallus XP_415932 468 51770 N275 S Y E A S S G N K T G E S A A
Frog Xenopus laevis NP_001083589 864 95245 S465 I N S G F S T S N D G S S S G
Zebra Danio Brachydanio rerio XP_002662240 560 63126 K345 S Y I Q K T D K G T T Q T K S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.3 92 73.3 N.A. 69.9 68.3 N.A. 23.1 25.4 26 30.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 92.4 94.2 79.3 N.A. 78.2 77.8 N.A. 32.9 45 37 44.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 73.3 N.A. 0 73.3 N.A. 0 33.3 13.3 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 73.3 N.A. 6.6 86.6 N.A. 6.6 40 20 40 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 0 0 0 0 0 0 0 10 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 0 10 0 0 10 10 10 10 0 0 % D
% Glu: 0 0 60 40 10 10 50 10 10 0 10 50 0 10 10 % E
% Phe: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 10 0 0 10 0 10 0 50 0 50 0 30 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 10 0 30 0 % H
% Ile: 10 0 10 10 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 10 10 0 10 10 0 0 0 0 10 0 % K
% Leu: 0 0 0 0 0 10 0 0 0 10 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 0 0 0 0 10 10 0 0 0 0 10 30 % N
% Pro: 10 50 0 10 0 40 0 10 50 0 10 0 0 0 0 % P
% Gln: 0 0 0 10 0 0 0 0 0 0 0 10 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % R
% Ser: 70 20 20 0 10 20 0 60 0 10 0 10 30 20 20 % S
% Thr: 0 0 10 0 10 10 20 0 0 70 10 10 10 10 0 % T
% Val: 10 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % V
% Trp: 0 0 0 0 50 0 10 0 0 0 0 0 0 0 0 % W
% Tyr: 0 20 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _