KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP17L5
All Species:
10.61
Human Site:
T446
Identified Species:
38.89
UniProt:
A8MUK1
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A8MUK1
XP_001130437.1
530
59683
T446
F
L
Q
E
Q
N
K
T
K
P
E
F
N
V
R
Chimpanzee
Pan troglodytes
XP_001139436
530
59460
T446
F
L
Q
E
Q
N
K
T
K
P
E
F
N
V
R
Rhesus Macaque
Macaca mulatta
XP_001082678
530
59566
T446
F
L
Q
E
Q
N
K
T
K
P
E
F
N
V
R
Dog
Lupus familis
XP_540055
535
59169
P447
C
L
Q
E
C
N
R
P
K
P
E
L
N
V
R
Cat
Felis silvestris
Mouse
Mus musculus
Q61068
526
59054
A441
Q
K
Q
N
H
Q
K
A
G
Q
N
L
R
N
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VRP5
1085
118669
S837
H
R
N
P
F
S
S
S
K
P
S
T
D
S
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FPS4
859
94885
Q685
G
L
R
K
K
K
V
Q
R
R
E
R
L
S
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.5
96
53.6
N.A.
46.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
20.2
N.A.
N.A.
N.A.
Protein Similarity:
100
97.9
97.5
66.7
N.A.
62.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
31.4
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
66.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
73.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% A
% Cys:
15
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% D
% Glu:
0
0
0
58
0
0
0
0
0
0
72
0
0
0
0
% E
% Phe:
43
0
0
0
15
0
0
0
0
0
0
43
0
0
0
% F
% Gly:
15
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% G
% His:
15
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
15
0
15
15
15
58
0
72
0
0
0
0
0
0
% K
% Leu:
0
72
0
0
0
0
0
0
0
0
0
29
15
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
15
15
0
58
0
0
0
0
15
0
58
15
0
% N
% Pro:
0
0
0
15
0
0
0
15
0
72
0
0
0
0
15
% P
% Gln:
15
0
72
0
43
15
0
15
0
15
0
0
0
0
0
% Q
% Arg:
0
15
15
0
0
0
15
0
15
15
0
15
15
0
58
% R
% Ser:
0
0
0
0
0
15
15
15
0
0
15
0
0
29
0
% S
% Thr:
0
0
0
0
0
0
0
43
0
0
0
15
0
0
29
% T
% Val:
0
0
0
0
0
0
15
0
0
0
0
0
0
58
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _