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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SERPINE3
All Species:
4.55
Human Site:
S412
Identified Species:
12.5
UniProt:
A8MV23
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A8MV23
NP_001094790.1
424
46963
S412
C
L
S
S
N
K
G
S
F
V
H
Y
P
L
K
Chimpanzee
Pan troglodytes
XP_509786
499
54706
S487
C
L
S
S
N
K
G
S
F
V
H
Y
P
L
K
Rhesus Macaque
Macaca mulatta
XP_001109037
397
43920
G386
F
I
R
H
N
P
T
G
A
V
L
F
M
G
Q
Dog
Lupus familis
XP_851657
397
43957
G386
F
I
R
H
N
P
T
G
A
V
L
F
M
G
Q
Cat
Felis silvestris
Mouse
Mus musculus
O35684
410
46329
E398
M
G
R
V
M
N
P
E
T
M
N
T
S
G
H
Rat
Rattus norvegicus
Q9JLD2
410
46259
E398
M
G
R
V
M
H
P
E
T
M
N
T
S
G
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90935
410
46511
A399
G
R
V
M
H
P
E
A
M
N
T
S
G
H
D
Frog
Xenopus laevis
Q52L45
377
42679
K366
L
I
R
H
N
A
T
K
S
I
L
F
F
G
R
Zebra Danio
Brachydanio rerio
B0UYL8
417
46382
L405
Q
I
S
T
G
S
L
L
F
I
G
R
V
V
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.7
29.7
29.4
N.A.
28.5
28.2
N.A.
N.A.
27.5
26.1
42.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
83.7
47.4
46.9
N.A.
52.8
53
N.A.
N.A.
52.3
44
60.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
13.3
13.3
N.A.
0
0
N.A.
N.A.
0
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
33.3
33.3
N.A.
13.3
13.3
N.A.
N.A.
13.3
33.3
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
12
0
12
23
0
0
0
0
0
0
% A
% Cys:
23
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% D
% Glu:
0
0
0
0
0
0
12
23
0
0
0
0
0
0
0
% E
% Phe:
23
0
0
0
0
0
0
0
34
0
0
34
12
0
0
% F
% Gly:
12
23
0
0
12
0
23
23
0
0
12
0
12
56
0
% G
% His:
0
0
0
34
12
12
0
0
0
0
23
0
0
12
23
% H
% Ile:
0
45
0
0
0
0
0
0
0
23
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
23
0
12
0
0
0
0
0
0
23
% K
% Leu:
12
23
0
0
0
0
12
12
0
0
34
0
0
23
0
% L
% Met:
23
0
0
12
23
0
0
0
12
23
0
0
23
0
0
% M
% Asn:
0
0
0
0
56
12
0
0
0
12
23
0
0
0
12
% N
% Pro:
0
0
0
0
0
34
23
0
0
0
0
0
23
0
0
% P
% Gln:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
23
% Q
% Arg:
0
12
56
0
0
0
0
0
0
0
0
12
0
0
12
% R
% Ser:
0
0
34
23
0
12
0
23
12
0
0
12
23
0
0
% S
% Thr:
0
0
0
12
0
0
34
0
23
0
12
23
0
0
0
% T
% Val:
0
0
12
23
0
0
0
0
0
45
0
0
12
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
23
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _