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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SERPINE3 All Species: 2.42
Human Site: T107 Identified Species: 6.67
UniProt: A8MV23 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A8MV23 NP_001094790.1 424 46963 T107 L P T S S Q G T E M E L A C S
Chimpanzee Pan troglodytes XP_509786 499 54706 A182 L P T S S Q G A E M E L A C S
Rhesus Macaque Macaca mulatta XP_001109037 397 43920 G89 R Y G V N G V G K I L K K I N
Dog Lupus familis XP_851657 397 43957 G89 R Y G V N G V G K V L K K I N
Cat Felis silvestris
Mouse Mus musculus O35684 410 46329 E101 S N M A S A E E N Q Y V M K L
Rat Rattus norvegicus Q9JLD2 410 46259 E101 S S M V S A E E G Q Y V M K I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90935 410 46511 S102 D M A T T E E S H Y V L N M A
Frog Xenopus laevis Q52L45 377 42679 N69 A V K D L H S N F Q T L N A E
Zebra Danio Brachydanio rerio B0UYL8 417 46382 S107 P Q G D L A N S S E G L R L Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.7 29.7 29.4 N.A. 28.5 28.2 N.A. N.A. 27.5 26.1 42.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 83.7 47.4 46.9 N.A. 52.8 53 N.A. N.A. 52.3 44 60.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 0 0 N.A. 6.6 6.6 N.A. N.A. 6.6 6.6 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 26.6 26.6 N.A. 20 13.3 N.A. N.A. 40 6.6 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 12 12 0 34 0 12 0 0 0 0 23 12 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 23 0 % C
% Asp: 12 0 0 23 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 12 34 23 23 12 23 0 0 0 12 % E
% Phe: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % F
% Gly: 0 0 34 0 0 23 23 23 12 0 12 0 0 0 0 % G
% His: 0 0 0 0 0 12 0 0 12 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 12 0 0 0 23 12 % I
% Lys: 0 0 12 0 0 0 0 0 23 0 0 23 23 23 0 % K
% Leu: 23 0 0 0 23 0 0 0 0 0 23 56 0 12 12 % L
% Met: 0 12 23 0 0 0 0 0 0 23 0 0 23 12 0 % M
% Asn: 0 12 0 0 23 0 12 12 12 0 0 0 23 0 23 % N
% Pro: 12 23 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 12 0 0 0 23 0 0 0 34 0 0 0 0 12 % Q
% Arg: 23 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % R
% Ser: 23 12 0 23 45 0 12 23 12 0 0 0 0 0 23 % S
% Thr: 0 0 23 12 12 0 0 12 0 0 12 0 0 0 0 % T
% Val: 0 12 0 34 0 0 23 0 0 12 12 23 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 23 0 0 0 0 0 0 0 12 23 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _