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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPTX
All Species:
14.55
Human Site:
Y128
Identified Species:
35.56
UniProt:
A8MV57
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A8MV57
XP_943629
137
15138
Y128
L
T
Y
E
D
N
G
Y
V
V
T
K
P
K
V
Chimpanzee
Pan troglodytes
XP_513916
223
25403
Y214
L
N
Y
E
I
R
G
Y
V
I
I
K
P
L
V
Rhesus Macaque
Macaca mulatta
XP_001117234
223
25296
Y214
L
N
Y
E
I
K
G
Y
V
I
I
K
P
L
V
Dog
Lupus familis
XP_545746
318
35124
E309
L
R
Y
E
T
R
G
E
V
F
L
K
K
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8R1M8
219
24520
Y210
L
N
Y
E
D
N
G
Y
V
V
I
K
P
K
L
Rat
Rattus norvegicus
Q6TA48
219
24313
Y210
L
T
Y
E
E
N
G
Y
V
V
T
K
P
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521709
287
31507
F275
L
N
W
E
S
L
S
F
E
N
R
G
Y
V
V
Chicken
Gallus gallus
NP_001034653
227
25642
D214
L
R
Y
E
A
K
G
D
V
V
V
K
P
R
L
Frog
Xenopus laevis
Q07203
238
27066
Q214
L
Q
Y
E
L
R
G
Q
A
T
T
Q
P
K
R
Zebra Danio
Brachydanio rerio
NP_001108387
223
25042
F204
D
R
V
K
G
N
V
F
D
W
N
T
I
K
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.8
31.3
22.3
N.A.
37.9
40.1
N.A.
26.4
30.8
27.3
26
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
42.1
41.7
31.1
N.A.
47
47.9
N.A.
34.8
37.8
39
37.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
60
60
40
N.A.
80
86.6
N.A.
20
53.3
46.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
66.6
66.6
53.3
N.A.
86.6
100
N.A.
33.3
66.6
53.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
20
0
0
10
10
0
0
0
0
0
0
% D
% Glu:
0
0
0
90
10
0
0
10
10
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
20
0
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
80
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
20
0
0
0
0
20
30
0
10
0
0
% I
% Lys:
0
0
0
10
0
20
0
0
0
0
0
70
10
50
0
% K
% Leu:
90
0
0
0
10
10
0
0
0
0
10
0
0
20
40
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
40
0
0
0
40
0
0
0
10
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
70
0
0
% P
% Gln:
0
10
0
0
0
0
0
10
0
0
0
10
0
0
0
% Q
% Arg:
0
30
0
0
0
30
0
0
0
0
10
0
0
10
10
% R
% Ser:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% S
% Thr:
0
20
0
0
10
0
0
0
0
10
30
10
0
0
0
% T
% Val:
0
0
10
0
0
0
10
0
70
40
10
0
0
10
40
% V
% Trp:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
80
0
0
0
0
50
0
0
0
0
10
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _