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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIGD1C
All Species:
6.67
Human Site:
S23
Identified Species:
18.33
UniProt:
A8MV81
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A8MV81
NP_001103089.1
97
11079
S23
L
S
R
L
I
R
K
S
R
D
S
P
F
V
P
Chimpanzee
Pan troglodytes
XP_001138606
87
9467
S18
S
Y
E
E
Y
Q
G
S
K
L
I
R
K
A
K
Rhesus Macaque
Macaca mulatta
XP_001115209
93
10170
A24
G
S
K
L
I
R
K
A
K
E
A
P
F
V
P
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q76I25
96
10806
S25
L
L
R
K
S
R
D
S
P
F
V
P
V
G
M
Rat
Rattus norvegicus
Q8VH49
93
10283
A24
G
S
K
F
I
R
K
A
R
E
T
P
F
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521708
140
15843
S66
V
S
K
L
L
R
K
S
Q
D
F
P
F
I
P
Chicken
Gallus gallus
NP_001026128
95
10640
F26
T
S
K
L
L
R
K
F
K
E
T
P
F
V
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956394
99
11142
G26
Q
N
P
F
V
P
A
G
M
A
G
F
F
A
I
Tiger Blowfish
Takifugu rubipres
NP_001072104
87
9794
N18
F
L
R
K
A
K
E
N
P
F
V
P
V
G
M
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56.7
55.6
N.A.
N.A.
81.4
58.7
N.A.
43.5
54.6
N.A.
55.5
52.5
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
72.1
75.2
N.A.
N.A.
90.7
75.2
N.A.
58.5
77.3
N.A.
75.7
72.1
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
60
N.A.
N.A.
33.3
60
N.A.
60
53.3
N.A.
6.6
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
93.3
N.A.
N.A.
33.3
86.6
N.A.
93.3
86.6
N.A.
20
33.3
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
0
12
23
0
12
12
0
0
23
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
12
0
0
23
0
0
0
0
0
% D
% Glu:
0
0
12
12
0
0
12
0
0
34
0
0
0
0
0
% E
% Phe:
12
0
0
23
0
0
0
12
0
23
12
12
67
0
0
% F
% Gly:
23
0
0
0
0
0
12
12
0
0
12
0
0
23
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
34
0
0
0
0
0
12
0
0
12
12
% I
% Lys:
0
0
45
23
0
12
56
0
34
0
0
0
12
0
12
% K
% Leu:
23
23
0
45
23
0
0
0
0
12
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
23
% M
% Asn:
0
12
0
0
0
0
0
12
0
0
0
0
0
0
0
% N
% Pro:
0
0
12
0
0
12
0
0
23
0
0
78
0
0
56
% P
% Gln:
12
0
0
0
0
12
0
0
12
0
0
0
0
0
0
% Q
% Arg:
0
0
34
0
0
67
0
0
23
0
0
12
0
0
0
% R
% Ser:
12
56
0
0
12
0
0
45
0
0
12
0
0
0
0
% S
% Thr:
12
0
0
0
0
0
0
0
0
0
23
0
0
0
0
% T
% Val:
12
0
0
0
12
0
0
0
0
0
23
0
23
45
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
0
0
12
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _