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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NCF1C All Species: 11.21
Human Site: S259 Identified Species: 27.41
UniProt: A8MVU1 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A8MVU1 NP_000256 366 41851 S259 P S M Y L Q K S G Q D V S Q A
Chimpanzee Pan troglodytes XP_001152639 390 44664 S283 P S M Y L Q K S G Q D V S Q A
Rhesus Macaque Macaca mulatta XP_001084055 390 44708 S283 P S M Y L Q K S G Q D V S Q A
Dog Lupus familis XP_849574 382 43672 T272 V V R K D D I T G Y F P S M Y
Cat Felis silvestris
Mouse Mus musculus Q09014 390 44679 G284 S M Y L Q K A G E E I T Q A Q
Rat Rattus norvegicus NP_446186 389 44661 G284 S M Y L Q K A G E E I T Q A Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001025880 388 45354 G284 S M Y L Q K S G E V N S P E K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001025242 410 47867 K288 F L C R T G E K K E V D A E R
Tiger Blowfish Takifugu rubipres NP_001027718 423 48760 R287 F L Q K A N K R E Q S E S S R
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783086 618 67562 S319 P G P G P G S S G R P Q P P V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.5 90.5 72.2 N.A. 75.9 76.3 N.A. N.A. 61.5 N.A. 50.4 49.4 N.A. N.A. N.A. 22.6
Protein Similarity: 100 93.5 91.5 78.8 N.A. 84.3 85 N.A. N.A. 76.8 N.A. 66 65.9 N.A. N.A. N.A. 34.4
P-Site Identity: 100 100 100 13.3 N.A. 0 0 N.A. N.A. 0 N.A. 0 20 N.A. N.A. N.A. 20
P-Site Similarity: 100 100 100 20 N.A. 13.3 13.3 N.A. N.A. 20 N.A. 26.6 20 N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 20 0 0 0 0 0 10 20 30 % A
% Cys: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 10 10 0 0 0 0 30 10 0 0 0 % D
% Glu: 0 0 0 0 0 0 10 0 40 30 0 10 0 20 0 % E
% Phe: 20 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % F
% Gly: 0 10 0 10 0 20 0 30 50 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 10 0 0 0 20 0 0 0 0 % I
% Lys: 0 0 0 20 0 30 40 10 10 0 0 0 0 0 10 % K
% Leu: 0 20 0 30 30 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 30 30 0 0 0 0 0 0 0 0 0 0 10 0 % M
% Asn: 0 0 0 0 0 10 0 0 0 0 10 0 0 0 0 % N
% Pro: 40 0 10 0 10 0 0 0 0 0 10 10 20 10 0 % P
% Gln: 0 0 10 0 30 30 0 0 0 40 0 10 20 30 20 % Q
% Arg: 0 0 10 10 0 0 0 10 0 10 0 0 0 0 20 % R
% Ser: 30 30 0 0 0 0 20 40 0 0 10 10 50 10 0 % S
% Thr: 0 0 0 0 10 0 0 10 0 0 0 20 0 0 0 % T
% Val: 10 10 0 0 0 0 0 0 0 10 10 30 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 30 30 0 0 0 0 0 10 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _