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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BECN1L1 All Species: 37.58
Human Site: S333 Identified Species: 59.05
UniProt: A8MW95 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A8MW95 XP_497740 441 49073 S333 G N H S Y L K S L T D D R T E
Chimpanzee Pan troglodytes XP_528814 431 48335 S323 G N H S Y L K S L T D D R A E
Rhesus Macaque Macaca mulatta XP_001105659 469 52227 S323 G N H S Y L K S L T D E G T E
Dog Lupus familis XP_547492 452 51366 S323 G N R S Y L K S L T N D P V E
Cat Felis silvestris
Mouse Mus musculus O88597 448 51515 S339 G N H S Y L E S L T D K S K E
Rat Rattus norvegicus Q91XJ1 448 51538 S339 G N H S Y L E S L T D K S K E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514527 394 45783 S285 G N H S Y L E S L T D K S K E
Chicken Gallus gallus Q5ZKS6 447 51416 S338 G N H S Y L E S L T D K S K E
Frog Xenopus laevis Q6GP52 445 51275 S336 G N H S Y L E S L T D K S K E
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres NP_001032963 447 51199 S338 G N H S Y L E S L T D K S K E
Fruit Fly Dros. melanogaster Q9VCE1 422 48852 V317 G N H S Y V E V L G E N R E L
Honey Bee Apis mellifera XP_392365 430 49618 A321 G N H S Y I E A L D Q H R E L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786368 415 47747 S310 G N H S H L E S L T D K S K Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M367 517 58486 V378 M G S Y P R I V D S N N E T Y
Baker's Yeast Sacchar. cerevisiae Q02948 557 63242 K394 G S F S K I K K R M V N S V E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.3 82 47.1 N.A. 55.7 55.3 N.A. 48.9 54.3 53.9 N.A. 52.1 37.1 41 N.A. 41.9
Protein Similarity: 100 95.2 84.8 62.8 N.A. 68.9 68.5 N.A. 63.7 67.3 67.8 N.A. 64.8 54.8 56.9 N.A. 58.5
P-Site Identity: 100 93.3 86.6 73.3 N.A. 73.3 73.3 N.A. 73.3 73.3 73.3 N.A. 73.3 46.6 46.6 N.A. 60
P-Site Similarity: 100 93.3 93.3 80 N.A. 80 80 N.A. 80 80 80 N.A. 80 73.3 66.6 N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. 24.3 22 N.A.
Protein Similarity: N.A. N.A. N.A. 44.8 40.9 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 7 0 0 0 0 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 7 7 67 20 0 0 0 % D
% Glu: 0 0 0 0 0 0 60 0 0 0 7 7 7 14 74 % E
% Phe: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 94 7 0 0 0 0 0 0 0 7 0 0 7 0 0 % G
% His: 0 0 80 0 7 0 0 0 0 0 0 7 0 0 0 % H
% Ile: 0 0 0 0 0 14 7 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 7 0 34 7 0 0 0 47 0 47 0 % K
% Leu: 0 0 0 0 0 74 0 0 87 0 0 0 0 0 14 % L
% Met: 7 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % M
% Asn: 0 87 0 0 0 0 0 0 0 0 14 20 0 0 0 % N
% Pro: 0 0 0 0 7 0 0 0 0 0 0 0 7 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 7 % Q
% Arg: 0 0 7 0 0 7 0 0 7 0 0 0 27 0 0 % R
% Ser: 0 7 7 94 0 0 0 74 0 7 0 0 54 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 74 0 0 0 20 0 % T
% Val: 0 0 0 0 0 7 0 14 0 0 7 0 0 14 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 80 0 0 0 0 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _