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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 8.79
Human Site: S133 Identified Species: 48.33
UniProt: A8MWC7 Number Species: 4
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A8MWC7 XP_002342421.1 184 20393 S133 R K L Q K Y S S D C E S I R R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001096356 219 24534 S167 R E L Q K Y S S D S E S T R R
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q99KS2 221 24349 T166 R E L Q K S A T S D S E A T G
Rat Rattus norvegicus Q3T1H2 221 24921 T166 R E L Q K Y T T H D S E A D R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001038718 289 32587 N238 S K G E M D V N D D V E F E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 64.3 N.A. N.A. 47.9 45.7 N.A. N.A. N.A. N.A. 22.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 70.3 N.A. N.A. 57.4 57 N.A. N.A. N.A. N.A. 34.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 80 N.A. N.A. 26.6 40 N.A. N.A. N.A. N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 86.6 N.A. N.A. 46.6 60 N.A. N.A. N.A. N.A. 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 20 0 0 0 0 0 40 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 20 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 20 0 0 60 60 0 0 0 20 0 % D
% Glu: 0 60 0 20 0 0 0 0 0 0 40 60 0 20 20 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 20 0 0 % F
% Gly: 0 0 20 0 0 0 0 0 0 0 0 0 0 0 20 % G
% His: 0 0 0 0 0 0 0 0 20 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 20 0 0 % I
% Lys: 0 40 0 0 80 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 80 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 20 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 20 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 80 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 80 0 0 0 0 0 0 0 0 0 0 0 0 40 60 % R
% Ser: 20 0 0 0 0 20 40 40 20 20 40 40 0 0 0 % S
% Thr: 0 0 0 0 0 0 20 40 0 0 0 0 20 20 0 % T
% Val: 0 0 0 0 0 0 20 0 0 0 20 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 60 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _